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Correlating the Measure of Retinal Vascular Density Through Angio-OCT with Calcium Score

Correlating the Measure of Retinal Vascular Density Through Angio-OCT with Calcium Score

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05624255
Acronym
ANOSCA
Enrollment
101
Registered
2022-11-22
Start date
2022-12-15
Completion date
2023-03-16
Last updated
2024-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Abnormalities, Retinal Vascular, Vascular Diseases

Brief summary

Recent case-control studies have proven that the retinal vascularization mirrors the cardiac vascularization: more the coronary network is altered, more the density of retinal vessels is reduced. No studies have yet been realised in primary prevention. This study aims to demonstrate a link between the density of the retinal vascularization and the calcium score, which is currently the gold standard for the classification of cardiovascular risk in primary prevention. Thus, a simple image of the retinal vascularization could predict the cardiovascular risk of a patient. OCT angiography would become a major aid in the classification of cardiovascular risk in asymptomatic patients.

Interventions

OTHEROphthalmologic consultation

Complete ophthalmologic examination including angio-OCT

Sponsors

Centre Hospitalier Universitaire de Besancon
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
40 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* Patients eligible for a calcium score as part of their standard treatment and volunteers for an ophthalmologic consultation

Exclusion criteria

* Pregnant women

Design outcomes

Primary

MeasureTime frameDescription
Correlation between retinal vascular density and calcium scoreDay 1Comparison between values of calcium score and presence of vascular abnormalities in retina. Calcium is scored as follows: * Coronary Artery Calcium \[CAC\] = 0 : very low risk * CAC = \[1-100\[ : low risk * CAC = \[100-400\[ : moderate risque * CAC = \[400-1000\[ : high risk * CAC = \> 1000 : very high risk

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026