Dental Caries in Children
Conditions
Keywords
Moringa, Star Anis, Indian Costus, Mouth wash, Streptococus Mutans
Brief summary
The goal of this randomized controlled trial is to compare three different types of mouthwash, Moringa, Star anis, and Indian Costus 90 children participated in this study divided into 3 groups according to the type of mouthwash used and then subdivided in each group into 3 subgroups according to the concentration of the mouthwash 5,10,15%. the children were asked to rinse with the mouthwash 3 times per day for 1 week. bacterial count for streptococcus mutans was measured before and after the use of mouthwash to see the most effective concentration.
Detailed description
The powdered of Moringa, Star anis, and Indian Costus leaves (250 g) were extracted using 90% ethanol then filtered using Whatman Filter paper No.1 and dried under reduced pressure using rota vapor. The crude ethanolic extract was (200 mg). ninety children will be randomly distributed into three groups (1,2,3) (30 children each). each group was divided into further 3 groups (10 children each) according to the concentration of each herbal mouthwash (5,10,15%). each participant will be given a new bottle of a specific effective amount of herbal extract to be used as a mouthwash. Children will be instructed to rinse with 5ml of mouthwash. All groups were instructed to rinse three times a day with specific mouthwash for each group for about one minute and participants will be advised to use the mouthwash for seven days. Collection of saliva samples Prior to the start of the experiment, samples of unstimulated saliva were taken when the child spit a suitable amount of unstimulated saliva in a sterile container in the morning before breakfast. Initial salivary samples were collected to establish base levels (S1) using selective culture media, The salivary samples (S2) were collected after one week of using the mouthwash when the child spit a suitable amount of unstimulated saliva in a sterile container in the morning before breakfast.
Interventions
using Moringa mouthwashes in 3 different concentrations (5,10,15%) twice per day for 7 days
DRUGstar anise mouthwash
using star anise mouthwash in 3 different concentrations (5,10,15%) twice per day for 7 days
DRUGIndian costus mouth wash
using Indian costus mouthwash in 3 different concentrations (5,10,15%) twice per day for 7 days
Sponsors
Nahda University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Masking description
blinded
Intervention model description
Randomized controlled trial
Eligibility
Sex/Gender
ALL
Age
6 Years to 12 Years
Healthy volunteers
Yes
Inclusion criteria
* \- Children with no systemic disease, no history of recent antibiotic administration (last 2 weeks), antimicrobial mouth-rinse (last 12 hours), topical fluoride treatment within 4 weeks prior to baseline, children with no untreated active carious lesion, no orthodontic appliance or with low caries index (DMF& def \< 4)
Exclusion criteria
* Children using antibiotics, medications or mouthwashes at the time of the study, children with oral or systemic disease, children undergoing any dental treatment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| bacterial count | 1 weak | decrease the count of streptococus mutans after use of the herbal mouthwash |
Countries
Egypt
Contacts
Primary ContactGhada Salem, Ass. Professor
Backup ContactMohamed Rashed, Ph.D
Outcome results
None listed