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Exploring Oxytocin Response to Meditative Movement

Exploring Oxytocin Response to Meditative Movement

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05621694
Enrollment
21
Registered
2022-11-18
Start date
2017-09-30
Completion date
2022-01-31
Last updated
2023-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Brief summary

This pilot study is designed to test effects of a single session of meditative movement (Tai Chi Easy) on older adults' blood pressure, perceptions of connection, mood, and oxytocin levels.

Detailed description

Endogenous oxytocin (the cuddle hormone) is associated with lowering blood pressure (BP), suggesting that finding ways to increase oxytocin even in the absence of social connection, may be beneficial. Meditative movement emphasizing breath, meditative state and flow-inducing movements holds potential for reducing BP, improving mood and releasing oxytocin. In a single-group pilot study we exposed 21 OAs with mild-moderate hypertension to a 50-minute Tai Chi Easy (TCE) (simplified Tai Chi/Qigong) session, collecting BP, saliva samples for oxytocin, and psychosocial measures (connection, mood) pre/post intervention.

Interventions

BEHAVIORALTai Chi Easy

A meditative movement practice that includes simple qigong movement/breath practices and single, repeated tai chi movements taught to generate a meditative state and flow

Sponsors

Arizona State University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE

Intervention model description

Meditative movement practice: Tai Chi Easy

Eligibility

Sex/Gender
ALL
Age
55 Years to 80 Years
Healthy volunteers
Yes

Inclusion criteria

* Age 55-80 --BP above 120/80 -

Exclusion criteria

* having a neurologic disorder such as Parkinson's, seizure disorder, multiple sclerosis, Alzheimer's disease * answered yes to one or more questions on the Physical Activity Readiness Questionnaire (PAR-Q). The PAR-Q is a seven-question assessment that determines one's readiness, safety and ability to engage in physical activity and is safely validated for older adults

Design outcomes

Primary

MeasureTime frameDescription
Change in Blood PressureChange from baseline (pre-intervention) blood pressure to immediately after the 50-minute interventionUsing blood pressure cuff, conducting two consecutive readings of systolic and diastolic

Secondary

MeasureTime frameDescription
Change in Profile of Mood States; Short FormChange from pre-intervention mood to immediately post-50-minute intervention pointUsing only subscales for depression and tension, 14 items with response format 0-4, reporting mean of responses, range 0-4 with higher scores indicating higher levels of depression and tension.
Change in perception of Connection (this is not a published scale, no formal name, created for this study)Change from pre-intervention to immediately after the 50-minute interventionTwo items assessing perception of connection with others and connection with self, score range
Change in Salivary OxytocinChange from pre-intervention to immediately after the 50-minute interventionSaliva collection pre and post-intervention

Other

MeasureTime frameDescription
Flow State Scaleimmediately after the interventionUsed to assess perceptions of the experience of flow while performing the Tai Chi Easy intervention. 36 items, Score range 36-80, high scores indicate greater sense of flow.
Meditative Movement Inventoryimmediately after the interventionScales that assess the experience of meditative state and breath focus during intervention, 11 items, score range 11-66 (or reported as a mean of the scores on the scale, then 1-6 range), with higher numbers indicating less breath focus and meditative state.
The De Jong Gierveld Loneliness Scalepre-intervention only6 items each scored either 0 (not at all) 1 (somewhat lonely) or 2 (more lonely), score is computed as a mean across items, range 0-6 with higher scores indicating more loneliness

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026