Irritable Bowel Syndrome
Conditions
Keywords
Carbohydrates, low FODMAP diet, components in the low FODMAP diet
Brief summary
The aim was aimed to investigate if all carbohydrate groups eliminated in the Low FODMAP diet are equally important in relieving gastrointestinal symptoms in IBS. in a randomized cross-over design to three different carbohydrate-modified diets: A) Low Polyol diet, B) Low FOS+GOS diet, and C) Low FODMAP diet for three months without wash-out-periods. Gastrointestinal symptoms, Quality of life was measured at baseline and after each intervention diet.
Detailed description
Low FODMAP diets contain 3 major types of carbohydrates to be avoided. The clasical diet is very difficult to maintain over longer periods of time. Therefore, we aimed to investigate if all carbohydrate groups in the Low FODMAP diet are equally important in relieving gastrointestinal symptoms in IBS. Patients diagnosed with IBS according to the Rome III criteria were randomised in a cross-over design to three different carbohydrate-modified diets: A) Low Polyol diet, B) Low FOS+GOS diet, and C) Low FODMAP diet for a total of three months without wash-out-periods. Gastrointestinal symptoms were assessed by the Birmingham IBS questionnaire and adequate relief (IBS-AR). Quality of life was measured by the IBS Quality of Life Scale questionnaire (IBS-QOL). All registrations were performed at baseline and after each intervention diet.
Interventions
OTHERLow FODMAP DIET = Diet with Low polyol, FOS and GOS
Low Polyol diet
Sponsors
Jens Rikardt Andersen
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Cross-over of 3 variations of the low FODMAP diet excluding 1 of the 3 components in every period
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* IBS diagnosed by the Rome III criteria and * referred to the clinic for treatment by diet
Exclusion criteria
* Dementia * lack of ability to speak Danish * additional chronic diseases prevailing participation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Birmingham IBS questionnaire and adequate relief (IBS-AR). | 3 months | Score in points (low score means few symptoms) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| IBS Quality of Life Scale questionnaire (IBS-QOL) | 3 months | Score in points (high score means better life satisfaction) |
Countries
Denmark
Outcome results
None listed