The Impact of Two-field or Three-field Lymphadenectomy on Overall Survival in Middle and Lower Thoracic Esophageal Squamous Cell Carcinoma: An Observational Study

The Impact of Two-field or Three-field Lymphadenectomy on Overall Survival in Middle and Lower Thoracic Esophageal Squamous Cell Carcinoma: A Single Center Retrospective Analysis

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05617352

Enrollment

1659

Registered

2022-11-15

Start date

2022-05-01

Completion date

2022-10-10

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal Cancer

Brief summary

To clarify the effect of Two-field or Three-field Lymphadenectomy on the survival of esophageal squamous cell carcinoma.

Interventions

DIAGNOSTIC_TESTSince the data were collected retrospectively, there were no interventions

Since the data were collected retrospectively, there were no interventions

Study design

Observational model

OTHER

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Inclusion criteria

* 1\. Men and women aged 18-85 years * 2\. Histologically confirmed primary thoracic esophageal squamous cell carcinoma, * 3\. Staging PT1b-4A, N0-3, M0 AJCC eighth edition * 4\. Excluding lymph node dissection \< 15, (meeting the guideline criteria) * 5\. The tumor located in the lower middle thoracic.

Exclusion criteria

* 1\. Patients with a history of previous thoracic and abdominal surgery that may affect lymphatic reflux * 2\. Patients with distant metastasis confirmed by imaging * 3\. Patients with obvious surgical contraindications.

Design outcomes

Primary

Measure	Time frame	Description
The number of lymph nodes	2010.1.1-2017.12.30	Surgical data were retrospectively collected

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026