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Antibiotic Therapy in Infections of the Diabetic Foot Syndrome

Antibiotische Therapie In Infektionen Des Diabetischen Fusssyndroms

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05616351
Acronym
DFO
Enrollment
80
Registered
2022-11-15
Start date
2022-10-12
Completion date
2023-04-30
Last updated
2024-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic Foot Infection

Keywords

diabetic foot syndrome, antibiotic therapy, soft tissue infection, osteomyelitis, bone infection

Brief summary

This retrospective study examines the surgical and antibiotic treatment of diabetic foot syndrome infections treated at the University Hospital Basel since 2019. It analyses the implementation of the hospital in-house guidelines published in 2019 with regard to antibiotic therapy in diabetic foot infections, taking into account clinical, microbiological and histopathological criteria. The defined endpoints are (i) fully compliant with internal policies, (ii) partially compliant with internal policies, and (iii) not compliant with internal policies. The recording of these proportions is descriptive.

Detailed description

This retrospective study examines the surgical and antibiotic treatment of diabetic foot syndrome infections treated at the University Hospital Basel since 2019. (In 2019 the departments of infectiology and orthopedics at the University Hospital Basel published recommendations with regard to the duration of antibiotic therapy in infections of the diabetic foot syndrome. This depends on whether a surgical intervention was performed and takes into account both the microbiological and the histopathological samples). Data that are routinely collected in everyday clinical practice and stored in the hospitals' medical records will be evaluated. The aim of this research project is to check the implementation of these recommendations. Inadequate use of antibiotics should thus be recognized. The study has the aspect of quality control.

Interventions

OTHERData collection in patients with diabetic foot syndrome and infections in the area of the foot

Data collection: on (surgical and antibiotic) treatment and implementation of the recommendations published 2019 with regard to the duration of antibiotic therapy.

Sponsors

University Hospital, Basel, Switzerland
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* soft tissue infection or bone infection (incl. osteomyelitis) in diabetic foot syndrome * inpatient stay at the University Hospital Basel between January 1st, 2019 and December 31st, 2021 * surgical intervention (amputation and/or debridement) * signed general consent

Exclusion criteria

* datasets without a diagnosis of the diabetic foot * no surgical intervention performed (amputation and/or debridement) * surgical interventions performed by disciplines other than orthopaedics/traumatology (e.g. vascular surgery) * infections in osteosynthesis material (implant or fracture-associated infections)

Design outcomes

Primary

MeasureTime frameDescription
Compliance with the hospital in-house guidelines for diabetic foot infections with regard to antibiotic treatmentone time assessment at baselineImplementation of the guidelines published in 2019 with regard to antibiotic therapy in diabetic foot infections, taking into account clinical, microbiological and histopathological criteria. The defined endpoints are (i) fully compliant with internal policies, (ii) partially compliant with internal policies, and (iii) not compliant with internal policies.

Secondary

MeasureTime frameDescription
Duration of antibiotic therapy (days)one time assessment at baselineDuration of antibiotic therapy
Relapse of diabetic foot infections (number)one time assessment at baselineRelapse of diabetic foot infections (number)

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026