Application of LARS Ligament in Bone Prosthesis Replacement

A Prospective, Real-world, Single-center, Cohort Study of LARS Ligaments in Bone Tumors

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05616182

Enrollment

100

Registered

2022-11-15

Start date

2024-12-30

Completion date

2032-02-28

Last updated

2024-01-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malignant Tumor

Brief summary

This is a single-center, prospective, real-world observational study designed to enroll all patients eligible for enrollment. Basic data, treatment methods, postoperative complications and limb function were collected. The differences in postoperative complications, postoperative limb function and so on between patients who underwent LARS ligament implantation and bone prosthesis replacement (ligament group) and patients who underwent bone prosthesis replacement (control group) were compared.

Detailed description

This is a single-center prospective real-world observational study of 100 eligible patients with bone tumors who are scheduled to undergo LARS ligament implantation and/or bone prosthesis replacement in Henan Cancer Hospital in the next 10 years. Basic data, treatment methods, postoperative complications and limb function were collected. The differences in postoperative complications, postoperative limb function and so on between patients who underwent LARS ligament implantation and bone prosthesis replacement (ligament group) and patients who underwent bone prosthesis replacement (control group) were compared.

Interventions

OTHERLARS ligament and bone prosthesis replacement was performed

To report the postoperative complications and limb function of patients who underwent LARS ligament and bone prosthesis replacement in Henan Cancer Hospital.

Study design

Observational model

OTHER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

Men and women of all ages are welcome. Pathologically confirmed in our hospital as a subtype of malignant tumor. He received LARS ligament and bone prosthesis replacement at our hospital.

Exclusion criteria

Not Applicable.

Design outcomes

Primary

Measure	Time frame	Description
Postoperative complications	From surgery to 24 months after surgery	Complications of patients undergoing LARS ligament and bone prosthesis replacement.
Limb function	Patients were enrolled until 24 months after surgery	Limb function was assessed using the Musculoskeletal Oncology Society (MSTS) scoring scale for seven items, namely movement, pain, stability, deformity, strength, functional activity, and emotional receptiveness. The highest possible score is 35, with 5 points allocated to each project.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026