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Evaluation of Pediatric Measles Cases in 2019: Single-Center Experience

Evaluation of Pediatric Measles Cases in 2019: Single-Center Experience

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05614791
Enrollment
40
Registered
2022-11-14
Start date
2019-01-01
Completion date
2020-05-30
Last updated
2024-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Measles

Keywords

Measles, Vaccine, Children, Vitamin A

Brief summary

Measles, can be prevented and eliminated by vaccination, is a highly contagious viral disease that can lead to serious complications, disability, and death. As a result of the World Health Organization (WHO) and United Nations International Children's Emergency Fund (UNICEF) strategic plans, the annual global incidence of measles decreased by 75% over the period 2000-2015, and the estimated global mortality rate fell by 73%. For the current 2019 period, the European and the Eastern Mediterranean Region has recorded respectively more than two-fold and 1.5-fold increase in reported measles cases. As it is known, no specific antiviral treatment exists for the measles virus therefore, vaccination is still the most effective method of preventing disease. The aim of this study was to evaluate the measles cases in districts where the refugees live quite intensely.

Detailed description

Measles, can be prevented and eliminated by vaccination, is a highly contagious viral disease that can lead to serious complications, disability, and death. As a result of the World Health Organization (WHO) and United Nations International Children's Emergency Fund (UNICEF) strategic plans, the annual global incidence of measles decreased by 75% over the period 2000-2015, and the estimated global mortality rate fell by 73%. For the current 2019 period, the European and the Eastern Mediterranean Region has recorded respectively more than two-fold and 1.5-fold increase in reported measles cases. As it is known, no specific antiviral treatment exists for the measles virus therefore, vaccination is still the most effective method of preventing disease. The aim of this study was to evaluate the measles cases in districts where the refugees live quite intensely. This retrospective study was consecutively enrolled children who were considered as suspicious measles case according to with clinical features and attended in Esenler Gynecology and Pediatrics Hospital Pediatric Clinic between 01 January-30 June 2019.

Interventions

None listed

Sponsors

Marmara University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
1 Months to 18 Years
Healthy volunteers
No

Inclusion criteria

* The suspicious case of measles * Measles/Rubella Case Notification and Laboratory request and result form and Measles/ Rubella Case Study form must be filled * Accept the informed consent form * Positive Measles Ig M and Measles Ig G laboratory test

Exclusion criteria

* Rejected the informed consent form

Design outcomes

Primary

MeasureTime frameDescription
Evaluate the effect of measles vaccination status on symptom durationbaselinecompare the groups symptom durations (day) who fully, partly or not vaccinated
Evaluate the effect of vitamin A treatment on symptom durationin the first month after the first symptom observedcompare the groups symptom durations (day) who get or not get vitamin A treatment

Secondary

MeasureTime frameDescription
Evaluate the effect of measles vaccination status on leucocyte countbaselinecompare the groups leucocyte count who fully, partly or not vaccinated
Evaluate the effect of vitamin A treatment on leucocyte countbaselinecompare the groups leucocyte count who get or not get vitamin A treatment

Other

MeasureTime frameDescription
Evaluate the effect of measles vaccination status on cost of measles casesin the first month after the first symptom observedcompare the groups costs (Turkish Lira) who fully, partly or not vaccinated
Evaluate the effect of vitamin A treatment on cost of measles casesin the first month after the first symptom observedcompare the groups costs (Turkish Lira) who get or not get vitamin A treatment

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026