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Study of the Angle Lambda and Ocular Dominance

Study of the Correlations Between the Ocular Dominance Depth, the Angle Lambda and the Fixation Disparity in Healthy Individuals

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05613517
Acronym
EPOLAF
Enrollment
76
Registered
2022-11-14
Start date
2022-11-25
Completion date
2024-02-28
Last updated
2025-09-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

No Eye Disorder

Keywords

Angle lambda, Ocular dominance, Fixation disparity, Pupillary axis, Line of sight

Brief summary

Anatomical ophthalmological connections and their dynamics are still debated in the scientific community. However, their considering is essential in many surgeries (strabismus, cataract, refractive...) or in clinical practice. The correlation between these biometric values would make it possible to refine the knowledge related to these landmarks and thus offer better ophthalmological management by integrating these variables into the clinical examination. The aim of the study is to analyze the correlation between the angle lambda and the ocular dominance depth in healthy individuals without ophthalmologic disorder. Then, seconds goals were defined as the study of the relation between the value of the angle lambda and the fixation disparity quantified with the Rousseau test. Relation between ocular dominance measured with the Guillon's test and the Hole-in-car test will also studied.

Detailed description

The angle lambda corresponds to the angle formed by the pupillary axis (line passing through the center of the pupil and perpendicular to the cornea) and the line of sight (broken line between the fixation point and the fovea and passing through the center of the pupil entrance). The angle kappa corresponds to the angle between the visual axis (line between the point of fixation and the fovea: area of the retina allowing precise vision) and the pupillary axis. The angle lambda and the angle kappa are very close, which is why the lambda angle is often equated with the kappa angle, both in practice and in the literature. The literature reports a non-null angle kappa ranged between 1.91° ± 0.14° and 5.73° ± 0.10° in the general population. Also, studies have reported a significantly greater angle on the left eye compared to the right eye. Moreover - because of the interpupillary difference - each eye perceives the same image from a different angle, resulting in a fixation disparity, defined as the angle of the residual deviation of the visual axes when the subject fixes and binocularly merges an image. In some cases, too high a value of the disparity can lead to a fixation disorder requiring orthoptic treatment. Anatomical ophthalmological connections and their dynamics are still debated in the scientific community. However, their considering is essential in many surgeries (strabismus, cataract, refractive...) or in clinical practice. The correlation between these biometric values would make it possible to refine the knowledge related to these landmarks and thus offer better ophthalmological management by integrating these variables into the clinical examination. The aim of the study is to analyze the correlation between the angle lambda and the ocular dominance depth and the fixation disparity in a healthy population without ophthalmologic disorder. Then, seconds goals were defined as the study of the relation between the value of the angle lambda and the fixation disparity quantified with the Rousseau test. Relation between ocular dominance measured with the Guillon's test and the Hole-in-car test will also studied.

Interventions

* orthoptic assessment (visual acuity, refraction, stereopsis test, Cover-test, evaluation of the disparity of fixation and ocular dominance, measurement of the inter-pupillary distance * ocular biometry * corneal topography * monocular photographs in photopic condition

Sponsors

URC-CIC Paris Descartes Necker Cochin
CollaboratorOTHER
Assistance Publique - Hôpitaux de Paris
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

\- Informed major subject not opposing to their participation in the study

Exclusion criteria

* Subject with strabismus or organic ophthalmologic pathology * Or presenting a visual acuity lower than 10/10th * Or with a history of eye surgery

Design outcomes

Primary

MeasureTime frameDescription
Value of the angle lambdaDay 0Semi-automatic digital method of measurement by eye photograph.
Ocular dominance depthDay 0Guillon's and Hole-In-Card tests.

Secondary

MeasureTime frameDescription
Guillon testDay 0Ocular dominance.
Fixation disparityDay 0Rousseau test.
Method using corneal topographyDay 0Compare the values of the lambda angle obtained using the semi-automatic method of measurement by ocular photography and the method using corneal topography.
Semi-automatic method of measurement by ocular photographyDay 0Compare the values of the lambda angle obtained using the semi-automatic method of measurement by ocular photography and the method using corneal topography.
Ocular dominance measurements quantified by the Hole-in-the-card methodDay 0Ocular dominance.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026