Descriptive Study of a Cohort of Orbital Solitary Fibrous Tumors

Orbital Solitary Fibrous Tumors: Description of a Case Series and Study of the Recurrence Rate

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05613244

Acronym

TFS-ORB

Enrollment

Registered

2022-11-14

Start date

2023-01-26

Completion date

2023-07-25

Last updated

2023-10-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orbital Tumor

Brief summary

Orbital solitary fibrous tumors are rare tumors with an intermediate potential of malignancy. Orbital solitary fibrous tumors' prognostic criteria are still poorly understood. Some patients with orbital solitary fibrous tumors have been treated at the Adolphe de Rothschild Foundation Hospital. This cohort will be studied to describe the recurrence rate and to identify predictive factors of recurrence or metastasis.

Interventions

OTHERPhone call

Patients will be asked to complete a questionnaire via a phone call

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 120 Years

Healthy volunteers

Inclusion criteria

* Patients treated at the Adolphe de Rothschild foundation hospital for an orbital solitary fibrous tumor between 01/01/2014 and 09/30/2020

Exclusion criteria

* Opposition of the patient (or of the relative if the patient is deceased) * Patients benefiting from a legal protection measure * Pregnant or breastfeeding woman

Design outcomes

Primary

Measure	Time frame	Description
Population characteristics	inclusion	descriptive statistics of each variable: age, sex, symptoms, duration of symptoms
Medical history	inclusion	descriptive statistics of each variable: history of previous biopsy or excision, previous intraoperative data,previous pathological data
Radiological lesion features	inclusion	descriptive statistics of each variable: laterality, orbital location, size and characteristics on preoperative orbital imaging
Pathological lesion characteristics	inclusion	descriptive statistics of each variable: presence of necrosis, presence of epithelioid morphology of these cells, presence of cellular atypia, description of the mitotic index, immunohistochemical study, proliferation factor
Intraoperative data	inclusion	descriptive statistics of each variable: complete or incomplete surgical removal, surgical removal 'in toto' or by fragments

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026