Esophageal Cancer
Conditions
Brief summary
The aim of the study is to investigate inter-observer variation in gross tumor volume (GTV) delineation of oesophageal cancer on different imaging modalities - CT, PET CT and MR.Twenty-three consecutive patients with esophageal cancer treated with preoperative or curative chemoradiotherapy were selected. All patients had CT, PET CT and MR imaging in treatment position prior to radiotherapy.Five experienced observers from our institution will independently delineate GTV on CT alone, MR alone, PET CT alone, on co-registered CT and MR and co-registered PET CT and MR. Inter-observer agreement, expressed in generalized conformity index (CIgen) and mean volumes of GTV will be calculated per patient and imaging modality.
Interventions
OTHERMR, PET CT
diagnostic method
Sponsors
Institute of Oncology Ljubljana
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* locally advanced esophageal cancer eligible for treatment with preoperative or curative chemoradiotherapy
Exclusion criteria
* contraindications for MR
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change of interobserver variability in target volume delineation on CT, PET CT and MR. | Through study completion, an average of 1 year. | To compare target volume delineation of esophageal cancer using CT, PET CT and MR with determining generalized conformity indexes and mean volumes of GTV. |
Countries
Slovenia
Outcome results
None listed