Non-small Cell Lung Cancer
Conditions
Keywords
disease self-management, mobile application, target therapy
Brief summary
The study's purpose is to understand the self-management needs of patients with NSCLC receiving targeted therapy, develop a disease self- management application (mHealth Application), and explore the effect of mHealth application on the self-efficacy and health status of patients receiving targeted therapy for NSCLC. This study adopts a two-group (pre-and-post-test) design experiment. This study is being conducted over a period of 3 years and is divided in two stages. This study enrolled patients with NSCLC in the outpatient clinic and ward of the Division of Chest Medicine in a northern medical center as the research participants. Stage 1 develop a disease self-management application and understands participants' needs by qualitative study. The participants are a purposive sample of 15-20 patients. Data discontinued when theme saturation is achieved. Stage 2 adopted convenient sampling to enroll 108 patients (54 in the experimental group and 54 in the control group) to evaluate the effectiveness of the disease self-management application. After participant's consent was obtained, this study performed the pre-test and randomized the participants. The experimental group received both routine care and the disease self-management App, while the control group received routine care and part of application. This study collected data before the patients received targeted therapy and in months 1, 3, 6, and 9 after treatment initiation.
Interventions
OTHERdisease self-management application
The mHealth application provide disease self-management knowledge and skills and also has the functions of level of skin toxicity warning, uploading photos of skin toxicity, and interacting with healthcare professionals.
Sponsors
Chang Gung Memorial Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* ≧20 years of age * diagnosed with advanced NSCLC * were epidermal growth factor, anaplastic lymphoma kinase...inhibitor-naive
Exclusion criteria
* had received other anti-cancer therapy * were difficulty with verbal expression or cognitive dysfunction
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| European Organization for Research and Treatment of Cancer 30-item core quality of life questionnaire | change from baseline at 1 month | assessing participants' quality of life |
| NCI-CTCAE (ver 5.0) guideline | change from baseline at 1 month | assessing participants' skin toxicity grade |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| knowledge and skills with disease self-management questionnaire | change from baseline at 1 month | assessing participants' knowledge and skill ability with disease self-management |
| disease self-efficacy questionnaire | change from baseline at 1 month | assessing participants' self-efficacy with disease self-management |
| Hospital Anxiety and Depression Scale | change from baseline at 1 month | assessing participants' anxiety and depression |
| Medical Outcomes Study-Social Support Survey | chang from baseline at 1 month | assessing participants' social support |
Contacts
Primary ContactKang Hua Chen, PhD
Outcome results
None listed