Laryngeal Edema
Conditions
Keywords
Post-extubation stridor, Intensive care unit, Ultrafast ultrasonography
Brief summary
In ICU, ventilatory weaning failure is common, accounting for up to 25% of extubations. These failures are largely due to swallowing disorders and laryngeal edema. Edema prevalence in ICU varies between 4 and 37%. Post-extubation stridor is a clinical sign of upper airway obstruction and may require urgent reintubation, which is associated with increased patient length of stay, morbidity and mortality. Identifying patients at risk is critical, and the need for reliable tools to predict the occurence of laryngeal edema is still relevant.
Interventions
OTHERUltrafast ultrasonography
Ultrasonography of the neck, patient in supine position, neck hyper-extended. Three different scanning planes containing several landmarks. Carried out in the 12h prior extubation.
Sponsors
Groupe Hospitalier du Havre
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adults, * Intubated and ventilated for more than 24h, * Filing mechanical ventilation weaning criteria.
Exclusion criteria
* Pregnant of breast-feeding woman, * Under guardianship patient, * History of laryngeal tumor, stroke, paralysis of recurrent nerve, swallowing disorders, * History of surgical laryngeal intervention or radiotherapy, * Unplanned extubation, * Opposition to take part in the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Correlation between laryngeal ultrafast ultrasonography and occurence of laryngeal edema | Within the 24 hours following extubation | A laryngeal edema is defined as a post-extubation stridor. Performance of ultrafast ultrasonography for laryngeal edema prediction in intensive care patients will be assessed with specificity, sensitivity, positive predictive value and negative predictive value. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Correlation between laryngeal ultrafast ultrasonography and occurence of swallowing disorders | Within the 24 hours following extubation | Performance of ultrafast ultrasonography for swallowing disorsders prediction in intensive care patients will be assessed with specificity, sensitivity, positive predictive value and negative predictive value. |
Countries
France
Contacts
Primary ContactClement Medrinal
Outcome results
None listed