Lymphedema, Breast Cancer
Conditions
Keywords
compression therapy, lymphedema, exercise
Brief summary
The aim of this study to investigate 24 hours of effects of remedial exercises with and without compression therapy on severity of lymphedema and symptoms of the lymphedema The present study is designed as a non-drug clinical trial. The patients will complete two remedial exercise sessions, one without and one with compression in a randomized order separated by a 3-day wash-out period.The main questions it aims to answer are 1. The 24 hour effects of remedial exercises with and without compression therapy on the severity of lymphedema are different in individuals with lymphedema associated with breast cancer surgery. 2. The 24 hour effects of remedial exercises with and without compression therapy on the symptoms of lymphedema are different in individuals with lymphedema associated with breast cancer surgery.
Interventions
OTHERRemedial exercise
Remedial exercise program will be taught by qualified physiotherapist. Patients will be practiced to the exercise 3 sets of 15 repetitions without compression. Patients will be monitored telephonically in the washout period for remain the routine activities.
OTHERCompression bandage
Multi-layered short stretch bandaging will be applied for 23 hour. Patients will be practiced to the exercise 3 sets of 15 repetitions with compression bandage. The bandage will be removed at the same time the next day. Patients will be monitored telephonically in the washout period for remain the routine activities.
Sponsors
Hacettepe University
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Clinical diagnosis of unilateral arm lymphedema related to breast cancer disease- Age between 18 and 75 years * 2 cm or greater difference between the affected and unaffected arms in women with breast cancer related lymphedema * At least 12 months after breast cancer surgery end
Exclusion criteria
* current recurrence of breast cancer * bilateral involvement * active infection * presence of metastases * diabetes mellitus * hypertension * pre-existing neuromusculoskeletal and neurological conditions * edema due to other reasons (e.g., primary lymphedema, lung and heart diseases)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Ultrasonographic measurements | Change in symptoms related to lymphedema from baseline up to end of 24 hour | Ultrasound imaging was performed using a 5-13-Megahertz linear probe. During the procedure, the participants will be seated with their forearms supinated and extended on a pillow. Measurements will be made bilaterally from 10 cm distal and proximal to the elbow bend, from the midpoint of the medial and lateral epicondyles, along the line parallel to the arm axis. |
| Circumference measurement | Change in symptoms related to lymphedema from baseline up to end of 24 hour | The severity of lymphedema between the two extremities will be measured by measuring the environment at 5 cm intervals. |
| Bioimpedance spectroscopy | Change in symptoms related to lymphedema from baseline up to end of 24 hour | The patient is in the supine position with his arms and legs not touching each other. This measurement will be made using the Impedimed L-Dex U 400 device. The reference point is the top of both hands and the dorsum of the foot. This measurement is made using superficial electrodes and there is no risk. The percentage of fluid will be calculated by making a measurement for both arms. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| symptoms of lymphedema | Change in symptoms related to lymphedema from baseline up to end of 24 hour | Four participant-reported lymphedema symptoms were assessed: swelling, heaviness, tightness commonly associated with BCRL. Using a 100 mm visual analogue scale (VAS), participants marked on it the extent to which they perceived their arm to be swollen, heavy or tight and pain during the past month, with 0 being not at all and 10 being extremely. |
Countries
Turkey (Türkiye)
Outcome results
None listed