The Feasibility and Safety of Head-up Cardiopulmonary Resuscitation in Patients With Non-traumatic Cardiac Arrest

The Feasibility and Safety of Head-up Cardiopulmonary Resuscitation in Patients With Non-traumatic Cardiac Arrest: Single Center Research

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05609357

Enrollment

Registered

2022-11-08

Start date

2022-11-04

Completion date

2023-12-31

Last updated

2023-08-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Arrest

Keywords

cardiac arrest, Head-up Cardiopulmonary Resuscitation

Brief summary

Head up CPR with impedance threshold device(ITD) and active compression-decompression (ACD) has been proved to improve both cerebral and coronary perfusion pressure during resuscitation in animal models. Increased rates of Spontaneous Circulation (ROSC) were also observed in cardiac arrest patients. The goal of this clinical trial is to learn about the feasibility and safety of Head-up Cardiopulmonary Resuscitation in patients with non-traumatic cardiac arrest. Participants will be received head-up CPR during resuscitation. The main question it aims to answer is if there is any adverse or unfavorable event during resuscitation.

Interventions

DEVICEHead-up Cardiopulmonary Resuscitation

Elevate patient's head to 30 degrees by EleGARD System during cardiopulmonary resuscitation

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Healthy volunteers

Inclusion criteria

* Non-traumatic cardiac arrest * Age ≥ 20

Exclusion criteria

* Trauma * Age \< 20 * Pregnancy * Irreversible death (e.g. liver mortis, rigor mortis, decapitation, transection and decomposition) * Disorder of cervical spine

Design outcomes

Primary

Measure	Time frame	Description
Number and portion of participants with serious or non-serious adverse event	Up to 1 day	e.g. event of fall, failure of intubation

Secondary

Measure	Time frame	Description
Number and portion of participants with repeated CPR	up to 1 day	—
Number and portion of participants with survival to emergency department discharge	up to 1 day	—
Number and portion of participants with sustained return of spontaneous circulation	Up to 1 day	sustained ROSC ≥ 20 minutes

Countries

Taiwan

Contacts

Primary ContactChih-Hsien Lin

47ienn@gmail.com+886972653698

Backup ContactWei-Ting Chen

biochip52@hotmail.com+88623123456#26283

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026