Body-Weight Trajectory
Conditions
Brief summary
Pharmacotherapy becomes an important and effective approach to improve body weight. However, it still remains unclear how to manage potential fluctuation after its cessation. Lifestyle change is the foundation and included as a part of clinical routine in real-world, therefore, we plan to conduct a prospective study to assess the impact of health lifestyle education and related lifestyle adherence on body weight in Chinese people who live with obesity or overweight and are off-pharmacotherapy trial. The aim of this study is to examine the impact of lifestyle education and related lifestyle adherence on body weight related parameters in 6 months from treatment. In addition, body weight related results will be described.
Detailed description
Novel pharmacotherapy is emerging, leading to substantial and sustained improvement in body weight compared with placebo in clinical trials. However, there is no evidence on management of body weight in real world setting after cessation of treatment. Body weight fluctuation is a pivotal difficulty for obese subjects who left off pharmacotherapy. It would be interesting to investigate the impact of lifestyle education and related lifestyle adherence in this clinical situation and explore factors associated with weight loss maintenance. Therefore, we will conduct a prospective study to assess the impact of lifestyle education and related lifestyle adherence on body weight in Chinese people who live with obesity or overweight and are off-pharmacotherapy trial. The aim of this study is to examine the impact of lifestyle education and related lifestyle adherence on body weight related parameters in 6 months from pharmacotherapy cessation. In addition, body weight related results will be described.
Interventions
BEHAVIORALLifestyle Education Program
A remotely delivered structured lifestyle education program adapted from conventional lifestyle interventions
Sponsors
Shanghai Zhongshan Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* All patients who completed a pharmacotherapy trial with clinically meaningful weight loss (≥5%) * Those who consent to this study
Exclusion criteria
* Those who do not consent to this study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in body weight | 6 months | To examine the change in body weight from baseline to 6 months following lifestyle education. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in blood lipids | 6 months | To examine the change in blood lipids from baseline to 6 months following lifestyle education. |
| Change in glycemic control | 6 months | To examine the change in glycemic control from baseline to 6 months following lifestyle education. |
| Change in blood pressure | 6 months | To examine the change in blood pressure from baseline to 6 months following lifestyle education |
Countries
China
Outcome results
None listed