Obesity
Conditions
Brief summary
The purpose of this study was to evaluate the efficacy of 2 capsules (500 mg per capsule, 1000 mg per day) of Grape King Probiotic Capsules per day in promoting fat excretion in obese patients by clinical human food test.
Detailed description
This experiment is carried out in a controlled manner. Before the subjects enter the research experiment, they need to follow their original lifestyle. The habits of maintaining a constant body weight for more than 2 weeks before the test, such as calorie balance in the diet and the amount of activity. Then enter the test to carry out the evaluation test of probiotics to the end. 60 subjects were randomized, 20 to placebo and 40 to probiotics. The subjects took two capsules of Grape King probiotics daily, a total of 1000 mg. Continue to take it for 4 weeks, and perform blood routine tests. Body composition detection, waist and hip circumference measurement, related index analysis and 24-hour dietary questionnaires, gut health questionnaires and stool samples were collected and analyzed for 4 weeks before and after treatment.
Interventions
Eat a capsule for once, and twice a day
Eat a capsule for once, and twice a day
Sponsors
Study design
Eligibility
Inclusion criteria
* male or female participants * aged 20-40 years old * body mass index in 25-27 kg/m2 * body fat \> 25% for men and \> 30% for women
Exclusion criteria
* cancer, chronic heart disease, use drugs which pharmacological effects may affect immunity * having systemic infections * using probiotics.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline fecel lipid weight at week 4 | Week0, Week4 | Compared the difference of fecel lipid weight level between the week 4 and 0 |
Countries
Taiwan