Salivary Alkaline Phosphatase as a Biomarker for Dental Caries in A Group of Egyptian Children With Different Growth Rates: A Descriptive Cross-Sectional Study

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05607251

Enrollment

Registered

2022-11-07

Start date

2023-01-31

Completion date

2023-04-30

Last updated

2022-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Caries in Children

Brief summary

Aim of the study: 1. Assess the correlation between salivary alkaline phosphatase levels and dental caries. 2. Assess the effect of growth of children on the levels of salivary alkaline phosphatase enzyme. 3. Assess the effect of growth of children on caries experience and severity.

Interventions

OTHERNo intervention

There is no intervention as this is an observational study

Study design

Observational model

OTHER

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

6 Years to 8 Years

Healthy volunteers

Yes

Inclusion criteria

* Children aged 6 to 8 years old. * Children with and without previous dental visits.

Exclusion criteria

* Children with any systemic or mental illness. * Children whose parents refuse to sign the informed consent. * Children who will not cooperate on participation

Design outcomes

Primary

Measure	Time frame	Description
Salivary Alkaline Phosphatase levels in children with and without dental caries	2 months	Measured by spectrophotometry (unit: U/L)

Secondary

Measure	Time frame	Description
Caries index	2 months	Measured by DMFT and deft (unit: scores)
Caries severity	2 months	Measured by ICDAS (unit: scores)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026