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Effects of Eccentric Potentiation Activation on Muscle Function

Effects of Multi-joint Eccentric Potentiation Maximal Contractions on Muscle Function

Status
Withdrawn
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05606276
Enrollment
0
Registered
2022-11-04
Start date
2022-11-01
Completion date
2024-03-01
Last updated
2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post Activation Potentiation

Brief summary

The purpose of this study is to examine the potentiation effects of 2 sets of multi-joint eccentric overload maximal contractions on muscle function.

Interventions

OTHEREccentric Exercise

Individuals will do a randomized crossover intervention involving maximal eccentric contractions (2 sets of 6 per leg; experimental condition)

Individuals will do a randomized crossover intervention involving cycling (active control) exercise

Sponsors

Brennan Thompson
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
SINGLE (Investigator)

Intervention model description

Following a familiarization session, subjects will be assigned to an order for performing both an eccentric and a cycle (sham) session (i.e., crossover design, the order being randomized). These will be performed 3-7 days apart.

Eligibility

Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
Yes

Exclusion criteria

* lower body surgery or injury in the last 12 months * have any neuromuscular disease * height \>76 inches tall * height \<54 inches tall * eccentric strength greater than 725 pounds * pregnant or plan to be pregnant in the duration of the protocol * don't do resistance exercise at least once per week * perform intense cardio or strength training \>4 days per week * Present with any other significant comorbid conditions that would impair the ability to participate in the exercise-based testing Inclusion criteria: * 18 - 30 years old * strength train lower body 1-3 times per week

Design outcomes

Primary

MeasureTime frameDescription
Vertical JumpBaseline (pretest)3 countermovement vertical jumps, with 30 seconds of rest between attempts
Isokinetic eccentric maximal strengthBaseline (pretest)Maximal eccentric strength on the Eccentron machine. 2 repetitions per time point

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026