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Stereotactic Margins in Localized Bronchial Cancer (T1/T2a, N0)

Stereotactic Margins in Localized Bronchial Cancer (T1/T2a, N0)

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05605236
Acronym
Stereotactic
Enrollment
300
Registered
2022-11-04
Start date
2020-02-16
Completion date
2022-07-16
Last updated
2023-12-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchial Cancer

Keywords

Bronchial cancer, Bronchopulmonary cancer, Stereotactic radiotherapy, Stereotactic CTV margins, Cell lung cancer, 3D radiotherapy

Brief summary

Bronchopulmonary cancer is the first cause of mortality in the world. We want to update the margins used in stereotactic radiotherapy, in the context of localized lung cancer, of non-surgical management. The investigators wish to redefine the stereotactic radiotherapy margins according to the histological type in localized non-small cell lung cancer. Indeed, these criteria were previously defined on a smaller cohort, in the context of 3D radiotherapy (mainly T3, T4 tumors). In addition, the incidence of radiation pneumonitis is highly dependent on the irradiated lung volume, which in turn depends on the CTV margins used.

Interventions

None listed

Sponsors

University Hospital, Strasbourg, France
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* Major subject (≥18 years old) * Subject operated on at HUS for T1/T2a N0 stage lung adenocarcinoma or squamous cell carcinoma before 30/09/2019 * CT scan available on the HUS imaging server or on CD * Subject who has not expressed opposition to the use of his or her data for research purposes

Exclusion criteria

* Subject who has expressed opposition to participating in the study * Impossibility to give the subject informed information (difficulties in understanding the subject, ...) * Subject under legal protection * Subject under guardianship or curatorship

Design outcomes

Primary

MeasureTime frame
Retrospective histological study of tumor cell dissemination around the tumorFiles analysed retrospectively from January 01, 2009 to December 31, 2019 will be examined

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026