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Smoking Cessation Study

Carbon Monoxide Breath Testing Prior to Total Joint Arthroplasty to Ascertain Smoking and Aid in Encouraging Smoking Cessation

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05602753
Enrollment
300
Registered
2022-11-02
Start date
2021-02-18
Completion date
2025-01-31
Last updated
2022-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Arthropathy, Smoking Cessation

Brief summary

The primary outcome of this study is to determine the true incidence of smokers among patients undergoing joint replacement and secondly, what percent are able to quit smoking before surgery under a structured cessation program with carbon monoxide breath testing. The investigators hypothesize that self-reported smoking status is underreported and that routine carbon monoxide breath testing will improve abstinence rates at the time of surgery.

Detailed description

This study looks at patients who have been referred to our clinic for a potential hip and knee joint replacement surgery. Once it has been determined that the patient requires surgical replacement of either their hip or knee and is placed on our surgical waitlist, the patient will be asked if he or she would like to participate in the study. The investigators would ask all patients, both self-declared smokers and non-smokers, to participate. This study would include completing a smoking history questionnaire and a noninvasive carbon monoxide breath test. While smoking status is already assessed in the McGill University Health Centre preoperative questionnaire, the investigators intend on expanding these questions in study participants to better quantify their nicotine exposure.

Interventions

BEHAVIORALLifestyle Counseling

Referring to Stop smoking hotline, given pamphlets to encourage quitting smoking, pharmacy guidance, and possible referral to smoking cessation clinic.

Sponsors

McGill University Health Centre/Research Institute of the McGill University Health Centre
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No

Inclusion criteria

* Adults ages 18-85 who require a primary total hip or knee replacement * Any gender * Smokers and non-smokers * Osteoarthritis, rheumatoid arthritis, avascular necrosis

Exclusion criteria

* Patients who require revision surgery * Previous fracture to affected area * Emergency surgery * Patients who do not understand, read or communicate in either French or English

Design outcomes

Primary

MeasureTime frameDescription
True incidence of smokers among patients undergoing joint replacement15 minutesThe percentage of subjects who declare themselves as smokers and non-smokers with elevated Co2 levels.

Secondary

MeasureTime frameDescription
To determine the incidence of patients who successfully quit smoking prior to surgery.20 minutesThe percentage of subjects who were able to quit smoking under a structured cessation program with Carbon monoxide breath testing.

Countries

Canada

Contacts

Primary ContactAdam Hart, MD
adam.hart@mgcill.ca514-934-1934
Backup ContactKaren Smith, CRA
karen.smith@muhc.mcgill.ca514-934-1934

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026