Sepsis, Sepsis Syndrome, Septic Shock
Conditions
Keywords
Immunophenotype
Brief summary
The popuse of this study is to assess the inflammatory immunophenotypes of sepsis patients are significantly correlated with prognosis, which may provide theoretical basis for precise immune regulation of sepsis.
Detailed description
The clinical characteristics and inflammatory/immune markers of sepsis patients were analyzed dynamically and followed up to one year after diagnosis. Through latent category analysis, cluster analysis and other inflammatory immunophenotypes, the clinical characteristics of different inflammatory immunophenotypes and their relationship with the long-term prognosis of sepsis were clarified.
Interventions
None listed
Sponsors
Southeast University, China
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Patients with sepsis 3 diagnostic criteria were admitted to ICU; Aged 18 or above; Within 24 hours of diagnosis. \-
Exclusion criteria
Malignant tumor; Autoimmune diseases; Diseases of the blood system; HIV infection; History of high-dose glucocorticoid use (hydrocortisone 200mg/d or other hormone with equivalent titer, more than one week); pregnancy \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| survival or death in 28 days | From date of randomization until the date of out of ICU or date of death from any cause, whichever came first, assessed up to 28 days | observe wether the patients is survival or death in 28 days |
Countries
China
Outcome results
None listed