Predictive Model
Conditions
Keywords
predicted model, depression, anxiety, elderly patient
Brief summary
Anxiety and depression in later life are highly prevalent, often appear as comorbid disorders, and have many adverse consequences for both the individual and society. Given the disease burden, the large influx of new cases, and the economic costs, efforts should be made to prevent the onset of anxiety and depression in later life. Preventive interventions are likely to become more cost effective when they are targeted at elderly who have been exposed to risk factors known to be predictive of the onset of anxiety and/or depression. As the population aging is speeding up, senile diseases have become a significant and severe public health problem, influencing national health. More than 20 million elderly patients undergo surgery each year in China, accounting for a quarter of the population who undergo surgery. Therefore, it is necessary to construct a predictive model of anxiety and depression in perioperative elderly hospitalized patients
Detailed description
More than 20 million elderly patients undergo surgery each year in China, accounting for a quarter of the population who undergo surgery. Therefore, it is necessary to construct a predictive model of anxiety and depression in perioperative elderly hospitalized patients. In 2015, the WHO introduced the concept of healthy ageing for global ageing, with a focus on the mental health of older people at its core. Previous studies have found a 31 percent risk of anxiety and 29 percent risk of depression in older perioperative patients. Therefore, optimizing perioperative mental health management in older patients remains one of the challenges facing clinicians.
Interventions
OTHERno intervention
no intervention
Sponsors
Peking University First Hospital
Peking University People's Hospital
Shanghai Zhongshan Hospital
Fudan University
First Affiliated Hospital of Guangxi Medical University
The Affiliated Hospital Of Guizhou Medical University
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Taihe Hospital
Capital Medical University
Beijing Tiantan Hospital
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
First Affiliated Hospital of Xinjiang Medical University
China-Japan Friendship Hospital
Sun Yat-sen University
Chinese PLA General Hospital
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. elective non-cardiac surgery, 2. American society of Aneshesiologists (ASA) classification Ⅰ \ Ⅲ, 3. patients over age 65.
Exclusion criteria
1. patient refused follow-up study, 2. missing data exceeding 20%, 3. went to ICU or died after surgery, 4. have a history of any mental disorders such as epilepsy, Parkinson's disease, depression, anxiety, sleep disorders, or are currently taking relevant intervention drugs 5) patients with severe deafness, dementia or speech impairment.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Depression | Depression within 7 days of surgery | Primary outcomes were depression Patient Health Questionnaire 9 (PHQ-9).The PHQ-9 is a nine-item questionnaire for screening on the presence of depressive symptoms and monitoring depression severity. Items were scored on a four-point scale with total scores ranging from zero to twenty-seven. Scores were defined as: ≥5 mild, ≥10 moderate, and ≥15 severe level of depression. The recommended screening cutoff was ≥10, corresponding with at least a moderate level of depression. The higher the score, the worse the situation. The total score ranges from 0 to 27, and higher scores indicate more depressive symptoms. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Anxiety | Anxiety within 7 days of surgery | The GAD-7 is a seven-item questionnaire for screening on the presence of generalized anxiety disorder and assessing its severity. Items were scored on a four-point scale with total scores ranging from zero to twenty-one. Scores were defined as: ≥5 mild, ≥10 moderate, and ≥15 severe anxiety. The recommended screening cutoff was ≥10, corresponding with at least a moderate level of anxiety. Higher scores mean more anxiety. |
Countries
China
Outcome results
None listed