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PENG vs. QLB vs. Lumbar ESPB in Total Hip Surgery

Comparison of Pericapsular Nerve Group Block, Quadratus Lumborum Block and Lumbar Erector Spinae Plane Block for Acute Pain Management in Total Hip Surgery: A Randomized Clinical Trial

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05600244
Enrollment
60
Registered
2022-10-31
Start date
2022-12-15
Completion date
2023-10-10
Last updated
2023-09-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ESPB, Pericapsular Nerve, Quadratus Lumborum, Total Hip Surgery

Brief summary

The aim of this study is to compare between Pericapsular Nerve Group Block, Erector Spinae Plane Block and Quadratus Lumborum Block for managing acute postoperative pain in patients undergoing total hip surgeries under spinal anesthesia.

Detailed description

Total hip surgeries are one of the most common major orthopedic procedures to improve patient's functional status and quality of life. However, despite these advantages, the immediate postoperative period can be associated with severe pain that delays mobilization and increases hospital stay and the risk of thromboembolic events. Various methods are used for postoperative pain management. Intravenous opioid agents are among them, but they may cause undesirable side effects, such as respiratory depression, sedation, constipation, allergic reaction, nausea, and vomiting. Thus, alternative techniques are preferred.

Interventions

PROCEDUREPENG block Technique

A linear probe will be used. Puncture will be performed in a lateromedial direction until the needle tip reached the plane between the iliopsoas tendon and periosteum and between the anterior inferior iliac spine and iliopubic eminence. After a negative aspiration test, 30 ml of bupivacaine 0.25% will be injected in the plane beneath the iliopsoas muscle

PROCEDURELumbar ESPB Technique

Using the out-plane technique, a 22G/80-mm block needle will be advanced until it reached the transverse process. 0.5-1 ml of the prepared local anesthetic solution, 30 ml bupivacaine 0.25% will be administered leading to hydrodissection to confirm the correct location. The needle will be repositioned by pulling back a few millimeters if resistance occurs when administering local anesthetic . All local anesthetic will be administered to this location between the transverse process and the erector spinae muscle

PROCEDURETransmuscular QLB-t block Technique

A convex transducer will be placed in the transverse plane on the flank of the patient cranial to the iliac crest. The 4th lumbar vertebral transverse process, erector spinae muscles, psoas muscle, transverse abdominis muscle, internal and externa oblique muscles, and the quadratus lumborum muscle will be identified. A 15 cm 22G insulated needle will be inserted on the posterior corner of the transducer. 30 ml bupivacaine 0.25% will be administered between the quadratus lumborum and psoas muscles into the fascial plane.

Sponsors

Kafrelsheikh University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Age 18-65 years * Both genders * Body mass index \< 40 kg/m\^2 * American Society of Anesthesiologists (ASA) physical status I-III * Posted for total hip surgeries under spinal anesthesia

Exclusion criteria

* The presence of contraindications or allergy to local anesthetic agents * Chronic use of opioids or corticosteroids * Infection at the puncture site * Coagulopathy * Psychiatric disorders (dementia or cognitive impairment.

Design outcomes

Primary

MeasureTime frameDescription
Total amount of rescue analgesia24 hours postoperativelyTotal amount of rescue analgesia in the form of morphine will be recorded

Secondary

MeasureTime frameDescription
First analgesic request24 hours PostoperativelyThe time to first request of rescue analgesia will be recorded
Pain level48 hours PostoperativelyPain level will be evaluated using numeric rating analogue scale (NRS), which ranges from 0 to 10 points, with 0 indicating no pain, 1-3 indicating mild pain, 4-6 indicating moderate pain, and 7-10 indicating severe pain.
Adverse events48 hours PostoperativelyAdverse events will be recorded (e.g., nausea, vomiting, hypotension and bradycardia)

Countries

Egypt

Contacts

Primary ContactMohammad F. Algyar, MD
mohammad.algaiar@med.kfs.edu.eg111645345

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026