Cardiac Surgery, Cardiovascular Diseases, Microplastics, Nanoplastics
Conditions
Brief summary
The exponential growth in plastic production/use translates into a parallel increase in environmental plastic waste, which is constantly degraded into microplastics and nanoplastics. Information on the effects of microplastics on human health is still preliminary. Cardiac surgery patients is a population high exposed to plastics. This observational study will obtain biological samples of cardiac surgery patients as a reference and vulnerable group of individuals highly exposed to microplastics and potentially more susceptible. The objective of this research is to be able to detect microplastics on blood and operation samples of cardiac surgery patients as well as their potential genotoxic and immunological damage.
Interventions
OTHERMicroplastics
Detection of microplastics as a yes/no value
Sponsors
Kun Hua
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Age ≥18 years * Elective cardiac surgery
Exclusion criteria
* Emergency surgery or limited-term surgery * Previous cardiac surgery * Previous severe liver disease * Pregnant or planning to become pregnant * Have a malignant tumor
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Detection of microplastics in human heart tissue and the blood | perioperative: preoperative and pro-/postoperative blood and intraoperative heart tissue | Detection of microplastics in human heart tissue and the blood undergoing cardiac surgery |
Contacts
Primary ContactKun Hua, M.D.
Outcome results
None listed