Hyperthyroidism, Iodine Toxicity, Osteoarthritis
Conditions
Brief summary
Povidone iodine (PI) solution is an antimicrobial solution that can be used at hip and knee arthroplasty cases. It contains iodine that may be absorbed by the body. This study aims to investigate any absorption caused by PI solution.
Interventions
PROCEDUREPI solution
3,000 cc of \<2% concentrated povidone iodine solution will be used as irrigation solution at primary hip/knee arthroplasty. The PI solution was left in the joint for 3 minutes.
PROCEDURESaline Solution
3,000 cc of 0.9% saline solution will be used as irrigation solution at primary hip/knee arthroplasty. The saline solution was left in the joint for 3
Sponsors
Ankara University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* All patients with hip/knee osteoarthritis who undergo primary arthroplasty
Exclusion criteria
* Patients with abnormal thyroid function tests in the preoperative period, a history of the previous thyroid-related disease.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Urine iodine level | postoperative first day | Urine iodine concentration |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Thyroid hormone | postoperative 14 days | Blood thyroid hormone levels including: TSH, T3 and T4 |
Countries
Turkey (Türkiye)
Contacts
Primary ContactHakan Kocaoglu, MD
Outcome results
None listed