ERAS in Liver Surgery

Enhanced Recovery After Surgery: Compliance to the Program in Liver Surgery and Factors Associated With Drop-out

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05597319

Acronym

ERASliver

Enrollment

126

Registered

2022-10-28

Start date

2019-01-01

Completion date

2021-09-30

Last updated

2022-10-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ERAS

Brief summary

Enhanced Recovery After Surgery (ERAS) Program (EP) is widely applied to obtain a reduction in post-operative length of hospital stay and a faster restoration of pre-operative patient conditions. However, in Western countries, adherence to EP in liver surgery is still difficult to achieve due to deep-rooted traditional practices. In our Institute, since 2019, EP has been applied pursuing 18/23 items identified by 2016 guidelines. At all consecutive patients who underwent elective liver surgery in our Institution, EP was proposed and their adherence to ERAS items was measured before, during and after surgery. Data were retrospectively collected and analysed, particularly focusing on EP items. Primary outcome was compliance to EP, defined as at least 80% of accomplished items per patient. Secondary outcome was adherence to each ERAS item, while tertiary outcome was detecting the variables associated with program drop out.

Interventions

PROCEDURELiver resection

Liver resection, different kind of according to pathology

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* patients candidates to surgery for benign or malignant liver disease * liver resection with curative intent

Exclusion criteria

* refusal to participate at the EP * incapability to acquire informed consent * cognitive impairment that can prejudice the patient comprehension of the EP * liver surgery with palliative or diagnostic intent or non-resective liver surgery * emergency surgery

Design outcomes

Primary

Measure	Time frame	Description
Compliance to ERAS program	32 months	Compliance to ERAS program was defined as at least 80% of accomplished items per patient

Secondary

Measure	Time frame	Description
Compliance to ERAS items	32 months	Compliance to each ERAS item singularly
Drop-out factors	32 months	Determining factors associated with ERAS program drop-out

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026