Preservation of Spontaneous Breathing in Patients Undergoing Thoracoscopic Surgery

Comparison of Thoracic Paravertebral Nerve Block Combined Laryngeal Mask Airway With Preservation of Spontaneous Breathing Versus General Anesthesia Using Double-lumen Endobronchial Intubation in Patients Undergoing Thoracoscopic Surgery:

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05595096

Enrollment

Registered

2022-10-26

Start date

2021-02-01

Completion date

2022-01-31

Last updated

2022-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracoscopic Surgery

Keywords

Spontaneous breathing anesthesia

Brief summary

the aim of this study is to evaluate the advantages of the non-intubation compared with intubation anesthesia on enhanced recovery after thoracoscopic surgery

Detailed description

All patients will be screened to determine eligibility for study entry, and the patients who meet the eligibility requirements will be informed about the study and potential risks. After giving written informed consent, The patients were randomly divided into non-intubation group and intubation group

Interventions

PROCEDUREGeneral anesthesia with preservation of spontaneous breathing

non-intubation group, thoracic paravertebral nerve block was performed before anesthesia induction,when the BIS value drops to between 40 and 60, laryngeal mask airway(LMA) is placed,and observation of breathing

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Intervention model description

non-intubation group: thoracic paravertebral nerve block was performed before anesthesia induction,after anesthesia induction laryngeal mask airway(LMA) is placed. intubation group:were given routine induction with double-lumen endotracheal intubation.

Eligibility

Sex/Gender

ALL

Age

18 Years to 69 Years

Healthy volunteers

Inclusion criteria

* age 18-69 years old * Body mass index (BMI) was 18-24 kg / m2 * American Society of Anesthesiologists' physical classification class I-II * The preoperative pulmonary function was normal

Exclusion criteria

* Severe cardiopulmonary disease * Severe nervous system diseases * Severe blood system diseases * Severe liver and kidney dysfunction * Conversion to thoracotomy

Design outcomes

Primary

Measure	Time frame	Description
the hospitalized stay	1 year	the hospitalized stay

Secondary

Measure	Time frame	Description
The postoperative complications	1 year	postoperative nausea and vomiting(PONV), pulmonary infection, atelectasis, sore throat, hoarseness
Visual analogue score (VAS) after operation;	1 year	Visual analogue score (VAS) was compared between the two groups

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026