Acute Respiratory Distress Syndrom (SARS-Cov 2)
Conditions
Brief summary
Sarcopenia is a risk factor for adverse outcome in critically ill patients. Sarcopenia might be estimated from muscle surface measure on tomodensitometry. The purpose of the study is to identify if muscle surfaces measured on thoracic tomodensitometry are associated with mortality in patients with acute respiratory distress syndrome due to SARS-Cov-2.
Interventions
OTHERData collection
Demographic data: Age, Sex, weight, height, main history and treatments. \- Biological data: CRP, PCT, albumin, pre-albumin
muscle area calculated on the T7 and T12 thoracic slices
Sponsors
Centre Hospitalier Universitaire Dijon
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patients hospitalized in intensive care for SARS-Cov-2 infection since january 2020 * Thoracic TDM within the 30 day preceding ICU admission and up to 24 hours after ICU admission
Exclusion criteria
* Pregnancy * Neuromuscular disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| measurement of muscle area at T7 level indexed in cm²/m². | At hospital admission | use of CT measurements to discriminate between the 2 groups (deceased versus alive) |
Secondary
| Measure | Time frame |
|---|---|
| Duration of mechanical ventilation | within the 28 days |
| Ventilator free days | within the 28 days |
| number of days in Intensive care unit | within the 28 days |
| number of days in hospital | within the 28 days |
Contacts
Primary ContactMaxime NGUYEN
Outcome results
None listed