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A Meta-analysis Comparing Toothbrushes on Plaque Removal and Gingival Health

A Meta-analysis Comparing Electric and Manual Toothbrushes on Plaque Removal and Gingival Health

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05594004
Enrollment
2929
Registered
2022-10-26
Start date
2022-04-01
Completion date
2022-07-29
Last updated
2022-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Plaque, Gingivitis

Brief summary

The aim of this analysis was to compare gingivitis- and plaque-reduction efficacy from randomized controlled trials (RCTs) up to six months long evaluating oscillating-rotating, sonic, and manual toothbrushes

Interventions

Oscillating-rotating electric toothbrush used twice daily

DEVICESonic electric toothbrush

Sonic electric toothbrush used twice daily

DEVICEManual toothbrush

Manual toothbrush used twice daily

Sponsors

Procter and Gamble
Lead SponsorINDUSTRY

Study design

Observational model
OTHER
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

Subjects were excluded from this study for the following reasons; * pregnancy, * rampant caries, * severe periodontitis, * at discretionary of the Principal Investigator.

Design outcomes

Primary

MeasureTime frameDescription
Number of Bleeding SitesUp to 6 months (26 weeks)Change from baseline as measured on number of bleeding sites ( via gingival bleeding index, Loe Silness index, Gingival Bleeding Index (GBI), Papillary bleeding index or Mazza gingival index).
Dental Plaque ScoresUp to 6 months (26 weeks)Change from baseline as measured by mean plaque score reduction from baseline (via Turesky's Modification of Quigley-Hein index, or Rustogi Modified Navy Plaque Index).

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026