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Cognitive Behavioral Therapy(CBT) in Treatment of Methamphetamine Use Disorder

The Efficacy of Cognitive Behavioral Therapy(CBT) in Treatment of Methamphetamine Use Disorder

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05593796
Enrollment
50
Registered
2022-10-25
Start date
2023-09-01
Completion date
2025-03-01
Last updated
2023-08-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Methamphetamine Abuse

Brief summary

The efficacy of cognitive behavioral therapy(CBT) in treatment of methamphetamine use disorder

Detailed description

Methamphetamine (MA) use is a serious public health concern in many countries and is second to cannabis as the most widely abused illicit drug in the world. Over the past few years; there is an alarming increase in crystal methamphetamine (Shabu) abuse in the Egyptian market and The Egyptian government is annoyed from this issue because youth within the age of productivity were targeted. Regular methamphetamine use can be associated with a range of psychiatric symptoms, particularly psychosis, anxiety, and depression. No FDA approved pharmacological treatments are available for Meth addiction up till now and despite great advances achieved in understanding the neurobiology of drug addiction, the therapeutic options are severely limited . Consequently, the only available treatment at present is psychosocial intervention. The effectiveness of CBT for other substance-use disorders (e.g. alcohol-, opioid- and cocaine-use disorders) has been well documented and as such this basic treatment approach has been applied to amphetamine-type stimulant (ATS)-use disorder . Currently, there is not enough evidence to establish the efficacy of CBT for amphetamine -type stimulant( ATS) -use disorders because of a paucity of high-quality research in this area. The present study will examine the efficacy of Cognitive behavioral therapy in reducing methamphetamine use in comparison to medical treatment usually taken in methamphetamine use disorder

Interventions

BEHAVIORALcognitive behavioral therapy

12 weekly, individual sessions of manual-guided CBT delivered by trained clinician .

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Intervention model description

In phase 0: . These patients will undergo toxicological and psychiatric assessment and will be screened using the inclusion and exclusion criteria. phase 1: treatment-as-usual (TAU)- Group offered usual treatment include detoxification, medical care. Clinician-delivered CBT-Group offered 12 weekly, individual sessions of manual-guided CBT (15) delivered by trained clinician . phase2: a follow-up at 3-month post treatment phase without treatment.

Eligibility

Sex/Gender
MALE
Age
15 Years to 50 Years
Healthy volunteers
No

Inclusion criteria

* patients who meet the criteria for methamphetamine use disorder according to Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM 5) (10) * aged of 15-49 years' old * more than 9 year of education * urine drug screening positive for methamphetamine

Exclusion criteria

* other Axis I disorder of DSM-V criteria such as bipolar disorder, schizophrenia, depression * Had a legal case pending resulting in inability to commit to 12 weeks of treatment. * Refusal to participate * poly drug dependence.

Design outcomes

Primary

MeasureTime frameDescription
increase in the addiction severity index for methamphetamine use disorder12 weeks0-1 No imminent problem 2-3 slight problem 4-5 moderate problem 6-7considerable difficulty

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026