Gastric Cancer Stage, Lymph Node Metastasis
Conditions
Keywords
gastric cancer, lymph node metastasis, maximum amplitude, prognostic factor
Brief summary
We initially selected a total of 1128 patients with primary gastric cancer who presented at Shandong Provincial Hospital between January 2018 and October 2022, and retrospectively collected their clinical and pathological data. And retrospectively analyzed preoperative baseline characteristics, preoperative laboratory tests, and postoperative pathological results for these patients
Interventions
DIAGNOSTIC_TESTcoagulation-related factors
We retrospectively evaluated the relationship between lymph node metastasis and coagulation-related factors in 516 patients with T4a stage gastric cancer.
Sponsors
Shandong Provincial Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
1. patients with primary gastric malignant tumors, 2. patients who underwent radical resection of gastric cancer, 3. patients with a postoperative pathology of adenocarcinoma or signet ring cell carcinoma according to the WTO pathological classification,
Exclusion criteria
1. patients who have distant metastases, such as liver or lung metastases, were found on preoperative ultrasound and computed tomography (CT) examinations, 2. patients who have received preoperative neoadjuvant chemotherapy, 3. patients who take anticoagulant drugs (such as aspirin) prior to surgery, 4. patients who had any previous coagulation disorder.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Preoperative coagulation-related factors (MA values) of patients | Three years | MA values(mm). Measure the data of preoperative MA values in 516 gastric cancer patients to see wether this indicator correlated with tumor stage in patients with gastric cancer. |
| Preoperative coagulation-related factors (platelet counts) of patients | Three years | Platelet counts（x10\^9/L). Measure the data of preoperative platelet counts in 516 gastric cancer patients to see wether this indicator correlated with tumor stage in patients with gastric cancer. |
| Preoperative coagulation-related factors (fibrinogen levels) of patients | Three years | Fibrinogen levels (g/L). Measure the data of preoperative fibrinogen levels in 516 gastric cancer patients to see wether this indicator correlated with tumor stage in patients with gastric cancer. |
| Preoperative coagulation-related factors (D-dimer) of patients | Three years | D-dimer (mg/L). Measure the data of preoperative D-dimer in 516 gastric cancer patients to see wether this indicator correlated with tumor stage in patients with gastric cancer. |
| Postoperative pathological results of tumor T stage. | Three years | Recording the postoperative pathological tumor T stage in 516 patients with gastric cancer. |
| Postoperative pathological results of tumor N stage. | Three years. | Recording the postoperative pathological tumor N stage in 516 patients with gastric cancer. |
Countries
China
Contacts
Primary ContactFeng Tian, Doctor
Backup ContactChangqing Jing, Doctor
Outcome results
None listed