Nociplastic Pain Symptoms and Sensory Profiles in Low Back Pain

Nociplastic Pain Measurement and Sensory Profiles in Patients with Acute and Chronic Low Back Pain: a Longitudinal Observational Cohort Study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05592405

Enrollment

103

Registered

2022-10-24

Start date

2023-06-01

Completion date

2025-12-01

Last updated

2025-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Central Sensitisation, Low Back Pain

Brief summary

Assessing associations between Sensory profiles and nociplastic pain symptoms, and assessing the prognostic value of sensory profiles in the development of nociplastic pain symptoms in a low back pain population.

Detailed description

Therefore, the investigators aims are: * The primary aim of the study is to assess associations between Sensory Profiles (Adolescent/Adult Sensory Profiles) and Nociplastic pain Symptoms, in the acute and chronic low back pain population. * The secondary aim is to assess the prognostic value of sensory profiles in the transition to central sensitisation and pain, in the acute and chronic low back pain population at twelve weeks.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* patients with non-specific LBP * with or without radiating pain * aged 18-65 years * able to read and understand the Dutch language

Exclusion criteria

* previous lumbar spinal surgery * radiculopathy or any specific cause of low back pain such as lumbar spinal stenosis, current malignancy, spondyloarthropathy, osteoporosis, spondylolisthesis, major trauma, infection, or systemic disease.

Design outcomes

Primary

Measure	Time frame	Description
Central sensitiszation QST	12 weeks follow-up	Quantitative sensory testing
Central senzitization CSI	12 weeks follow-up	Central sensitization inventory
Central sensitization PSQ	12 weeks follow-up	Pain sensitization questionnaire

Other

Measure	Time frame	Description
Demograpics	12 weeks	established prognostic factors for low back pain

Countries

Netherlands

Outcome results