Studying of Natural Constituents' Treatment of Plantar Warts

In-vitro and Randomized Controlled Clinical Studying of Natural Constituents' Anti-HPV Potential for Treatment of Plantar Warts Supported With in Silico Studies

Status

Completed

Phases

Early Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05592041

Enrollment

Registered

2022-10-24

Start date

2022-10-20

Completion date

2023-01-10

Last updated

2024-05-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Plantar Wart

Brief summary

Moringa banana nigella and Banna coat extract were prepared and formulated in the form of bi gel for transdermal delivery of these plant extracts. The formulation was prepared and charterized for organoleptic charters, morphology, and penetration efficacy. The optimised formulation was assessed clinically on patients suffering from plantar warts. The clinical study was phase 1 and interventional randomised allocation.

Interventions

DRUGBanaba Leaf Extract

a herbal extract in the form of Bigel

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

20 Years to 50 Years

Healthy volunteers

Inclusion criteria

* Male or female patient aged 18 years or more. * Clinical evaluation * Number of warts lower than 10 on the 2 feet and total diameter of warts lower than 10 cm

Exclusion criteria

* Patient suspected to be immunocompromised * Patient aged under 18 years * Patient refusing to sign the consent * Pregnant or lactating women

Design outcomes

Primary

Measure	Time frame	Description
Complete clinical remission of the warts	30 days	Number of warts (counts)
Clinical assessment of warts curement	30 days	Diameter of wart in cm

Secondary

Measure	Time frame	Description
Pain asssesment	30 days	pain was assesed by VAS scoring (0) the least to (5) highest

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026