Urinary Tract Infections
Conditions
Keywords
Urinary tract infection, Urine culture, Bacteriel growth, Antibiotics, PCR
Brief summary
The objective of this study is the detection, quantification, and resistance gene identification of pathogens by using the urine of patients with urinary tract infection (UTI) symptoms.
Interventions
DIAGNOSTIC_TESTUrine PCR testing
The urine PCR panel will be performed to evaluate the bacterial growth in the patient's urine who is admitted with acute urinary tract symptoms.
Sponsors
Vikor Scientific
Thermo Fisher Scientific, Inc
David Sheyn
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult men and women 60 years and older who have urinary tract infection * Can participate in the informed consent process * Presenting to the clinic with symptoms of UTI or cystitis with no recent history of UTI within the past 21 days * Able to provide sufficient urine sample volume via clean catch or catheterization for urinalysis, conventional urine culture, and PCR * Understand and are willing to comply with the study requirements. * Sample collection able to be sent out the same day via courier
Exclusion criteria
* Individuals under 60 years of age * Unable to provide informed consent * Urinary diversion of any type * Chronic indwelling urinary catheter * No recent history of UTI within the past 21 days * No antibiotic therapy within the past 21 days * No recent therapy with Phenazopyridine
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Time in hours from patient presentation to optimal antibiotic prescription | Up to 30 days | Time in hours from patient presentation to optimal antibiotic prescription will be evaluated both for urine culture and urine PCR panel utilization. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of patients with antibiotic change as measured by prescription records | Up to 30 days | In cases where the UTI cannot be treated with the first antibiotic, other antibiotics used for this purpose will be recorded. |
| Duration of antibiotic usage as measured by prescription records | Up to 30 days | Antibiotic usage duration will be recorded. |
| Antibiotic costs as measured by prescription records | Up to 30 days | Antibiotic costs spent for UTI treatment will be calculated. |
| Number of hospitalization related to UTI as measured by patients reports/medical records | Up to 30 days | Hospitalization related to UTI will be recorded. |
| Number of additional diagnostic procedures completed in relation to UTI as measured by patients reports/medical records | Up to 30 days | Additional diagnostic procedures completed in relation to UTI will be recorded. |
| Number of any HCP visits for same issue as measured by patients reports/medical records | Up to 30 days | Any visit to HCP for the same issue will be evaluated |
Countries
United States
Outcome results
None listed