Analgesia
Conditions
Brief summary
Perineal pain resulting from malignancy is usually severe. Pain can be related to the malignancy or as a complication related to the treatment. several modalities are adopted to control such pain starting from medical management to interventional pain procedures.
Detailed description
Perineal pain resulting from malignancy is usually severe. Pain can be related to the malignancy or as a complication related to the treatment. several modalities are adopted to control such pain starting from medical management to interventional pain procedures. Ganglion impar block has been traditionally used for treatment of such perineal pain. Radiofrequency of sacral dorsal root ganglia can be used as an alternative for pain control.
Interventions
PROCEDUREGanglion Impar Neurolysis
block of Ganglion Impar by neurolytic drug
PROCEDUREBilateral S2, S3 and S4 Pulsed radiofrequency
Bilateral S2, S3 and S4 Pulsed radiofrequency
Sponsors
National Cancer Institute, Egypt
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* patients aged 18-75 years * ASA II-III with perianal and perineal pain related to cancer
Exclusion criteria
* patient refusal * coagulation defects * abnormal kidney or liver functions * local infection at site of injection
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Visual analogue scale | 2 hours | the score of visual analogue scale score, with minimum score of 0 and maximum of 10, with higher scores meaning more severe pain |
Countries
Egypt
Outcome results
None listed