Posterior Lumbosacral Spine Fixation Surgeries
Conditions
Brief summary
As the posterior lumbosacral spine fixation surgeries are common spine procedures done nowadays due to different causes and as this spine procedure is mostly accompanied with moderate to severe postoperative pain, so it is necessary to find an effective and efficient postoperative analgesia for patients with this surgery.
Interventions
DRUGDexmedetomidine injection
1ug/kg dexmedetomidine plus 20 mL of bupivacaine 0.25%
20 ml of bupivacaine 0.25%,
DRUGnormal saline
20 ml of normal saline 0.9%.
Sponsors
October 6 University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
20 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* elective posterior lumbosacral spine fixation and fusion surgery due to different causes that diagnosed clinically and radiologically including MRI and Plain X ray
Exclusion criteria
* hypersensitivity to the drugs used in the study \[local anesthetics, non-steroidal anti-inflammatory drugs, opioids and the drug under investigation (dexmedetomidine)\] * patients with any contraindication to regional anesthesia as skin infections at the site of the block * history of bleeding disorders or receiving anticoagulant medications
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative visual analogue scale (VAS) | the first 24 hours postoperative | The visual analog scale (VAS) is a simple and often used method for evaluating variations in pain intensity. |
| Amount of post operative opioid consumption for the first 24 hours | the first 24 hours postoperative | Amount of total opioid consumption for 24 hours postoperative |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative visual analogue scale (VAS) | the second 24 hour postoperative | The visual analog scale (VAS) is a simple and often used method for evaluating variations in pain intensity. |
| Amount of post operative opioid consumption for the second 24 hours | the second 24 hour postoperative | Amount of total opioid consumption for the second 24 hours postoperative |
Countries
Egypt
Outcome results
None listed