Plasma Lipid Profile
Conditions
Brief summary
The goal of this clinical trial is to compare the effect of saturated fat intake from different source on cardiometabolic risk markers in healthy subjects. The main question it aims to answer are: -Does intake of saturated fat in the form of high-fat yogurt have a different effect on cardiometabolic risk factors than intake of the same amount from butter? In this study, in two periods of 4 weeks, the effect of receiving saturated fat from high-fat yogurt compared to receiving the same amount of saturated fat from butter and low-fat yogurt on the plasma concentration of lipids, cholesterol, insulin, and some inflammatory factors will be studied in healthy subjects.
Interventions
OTHERsaturated fat intake
Intake of saturated fat from yogurt and animal butter daily for 4-week period
Sponsors
Shahid Beheshti University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy people who do not use lipid-lowering, blood pressure control or diabetes medications
Exclusion criteria
* Taking supplements of omega-3 fatty acids, or antioxidants
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Plasma lipid profile | 4 weeks | Plasma concentrations of cholesterol, high-density lipoprotein cholesterol, Low-density lipoprotein cholesterol, and triglyceride |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Glycemic measures | 4 weeks | Fasting plasma concentrations of glucose and insulin |
Other
| Measure | Time frame | Description |
|---|---|---|
| Inflammatory markers | 4 weeks | Plasma concentrations of c-reactive protein and interleukin 6 |
Countries
Iran
Outcome results
None listed