Intrauterine Growth Restriction
Conditions
Brief summary
The purpose of this study is to evaluate the effect of antenatal corticosteroid administration on umbilical artery Doppler velocimetry measurements in pregnancies complicated by IUGR.
Detailed description
This study was conducted with pregnant women who were likely to have preterm birth and were treated with antenatal corticosteroids. Betamethasone was used as an antenatal corticosteroid. UA Doppler measurements (PI, S/D ratio, RI) before antenatal corticosteroid administration and 24 and 48 hours after the last dose of corticosteroid administration were evaluated in pregnant groups complicated with IUGR and uncomplicated with IUGR and compared with each other.
Interventions
OTHERultrasonography
Umbilical artery Doppler evaluation by ultrasonography just before the first dose of antenatal corticosteroid, 24 hours and 48 hours after the last dose.
Sponsors
Marmara University
Merve Demir
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 49 Years
Inclusion criteria
pregnant women who were likely to have preterm delivery and were treated with antenatal corticosteroids.
Exclusion criteria
Pregnant women who had complicated pregnancy with fetal anomaly, who had multiple pregnancies, who left their pregnancy follow-up unfinished, and those under 18 years of age were excluded from the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| systolic:diastolic ratio (S/D ratio) | 2018-2019 | Peak systolic velocity/end diastolic velocity |
| pulsatility index (PI) | 2018-2019 | Pulsatility Index (PI) = (Peak systolic velocity - end diastolic velocity)/(time averaged maximum velocity) |
| Resistive Index (RI) | 2018-2019 | Resistive Index (RI) = (Peak systolic velocity - end diastolic velocity)/(peak systolic velocity) |
Countries
Turkey (Türkiye)
Outcome results
None listed