Consistency of Electrical Cardiometry and Pulmonary Artery Catheter

The Consistency of Cardiac Output Measured by Electrical Cardiometry and Pulmonary Artery Catheter in Cardiac Surgery Patients With Pulmonary Arterial Hypertension or Right Heart Dysfunction

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT05587400

Enrollment

199

Registered

2022-10-20

Start date

2022-07-27

Completion date

2024-12-31

Last updated

2022-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Arterial Hypertension, Right Ventricular Dysfunction

Brief summary

Currently, the gold standard method to estimate CO in patients with PAH or RV dysfunction is pulmonary artery catheter (PAC), however, the invasiveness and complexity of PAC has limited its usefulness in many clinical scenarios. By measuring the thoracic electrical bioimpedance, electrical cardiometry (EC) technique has been reported to noninvasively estimate cardiac output (CO) and other parameters related to cardiac contractility and fluid status in various cardiovascular disorders. However, in patients with pulmonary arterial hypertension (PAH) and/or right ventricular (RV) dysfunction, few study has been reported. The aim of this study is to evaluate the agreement between CO measured by PAC as the referenced method and CO measured by EC technique in patients with PAH and/or RV dysfunction.

Interventions

BEHAVIORALpassive leg raising

transfer a patient from semi-recumbent position to supine position with a 45° leg lifting

DRUGdobutamine test

infusion dobutamine

DRUGinhaled nitric oxide

nitric oxide inhalation

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* adult cardiac surgery patients * pulmonary artery hypertension and/or right heart dysfunction * mechanical ventilation

Exclusion criteria

* life threatening arrhythmia * severe valve regurgitation * left ventricular ejection fraction less than 30% * patients with mechanical circulatory support

Design outcomes

Primary

Measure	Time frame	Description
cardiac output by pulmonary artery catheter	5minutes after the patients was sedated	measuring cardiac output using pulmonary artery catheter
cardiac output by electrical cardiometry	5minutes after the patients was sedated	measuring cardiac output using electrical cardiometry

Countries

China

Contacts

Primary ContactZhe Luo, PhD

luo.zhe@zs-hospital.sh.cn02164041990

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026