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Perfusion Index vs Positional Hemodynamic Changes to Predict Hypotension After Spinal Anaesthesia in Caesarean Section

Comparative Study Between the Perfusion Index and Positional Haemodynamic Changes for Prediction of Hypotension After Spinal Anaesthesia in Caesarean Section

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05587153
Enrollment
80
Registered
2022-10-19
Start date
2022-07-15
Completion date
2022-12-30
Last updated
2022-12-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post Spinal Hypotension

Brief summary

Comparative Study between the Perfusion Index and Positional Haemodynamic Changes for Prediction of Hypotension after Spinal Anaesthesia in Caesarean Section

Detailed description

Hypotension following spinal anaesthesia may cause maternal dizziness, nausea, vomiting and fetal acidosis, administration of prophylactic vasopressor agents in pregnant women may cause undesirable effects on the mother and fetus. Perfusion index is the ratio of a pulsatile to a non-pulsatile fraction of blood volume. The increase of the pulsatile fraction manifested during vasodilatation corresponds to a higher PI. So, the patients with a higher PI have a higher risk for post-spinal hypotension. Elevated sympathetic activity before neuraxial anaesthesia was associated with a higher risk for post-spinal hypotension. The significant variability in haemodynamic after the positional change indicates higher sympathetic activity. The high the rise in autonomic activity, the higher the risk for post-spinal hypotension AIM OF THE WORK: Prediction of hypotension after spinal anaesthesia in caesarean section either by perfusion index and positional haemodynamic changes Grouping: All the recruited patients will be assessed by perfusion index. and by positional haemodynamic changes

Interventions

OTHERperfusion index in all parturient recruited for the study

Using perfusion index and positional hemodynamic changes for the prediction of postspinal hypotension in all parturient recruited for the study

Sponsors

Zagazig University
Lead SponsorOTHER_GOV

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* Parturient acceptance. * American Society of Anesthesiologists (ASA) II * arturient with be gestational age \>36 weeks and \<41 weeks. * Body mass index (BMI) ≤35kg/m2 * elective caesarean section delivery

Exclusion criteria

* preeclampsia * eclampsia, * gestational diabetes * Contraindication to regional anaesthesia as allergy, coagulation abnormalities or infection in site of injection.

Design outcomes

Primary

MeasureTime frameDescription
Prediction of post-spinal hypotension using PI6 monthsTo correlate between perfusion index and hypotension after spinal anaesthesia in caesarean section

Secondary

MeasureTime frameDescription
Prediction of post-spinal hypotension using positional hemodynamic changes6 monthsTo correlate between positional haemodynamic changes and hypotension after spinal anaesthesia in caesarean section

Countries

Egypt

Contacts

Primary ContactRamy M Husin, M.B.B. Ch
ramy23m@gmail.com01128601089
Backup ContactNaglaa F Abdelhaleem
nogaahmedkareem.fa@gmail.com01003103036

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026