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3 Snip Punctoplasty With and Without Mitomycine C.

Comparative Study on 3 Snip Punctoplasty With and Without Mitomycine C in the Management of Punctual Stenosis or Occlusion

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05586620
Enrollment
18
Registered
2022-10-19
Start date
2021-06-01
Completion date
2022-06-10
Last updated
2022-10-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Punctal Stenosis

Brief summary

Punctal stenosis is a progressive constriction of the puncta with resultant epiphora. One of the most effective treatment options is 1- to 4-snip punctoplasty combined with or without Mitomycin-C.

Interventions

PROCEDURE3-snip punctoplasty

punctoplasty, more commonly known as watery eye surgery, is an ophthalmic surgical procedure performed to correct punctal stenosis (a condition that causes tears to overflow from the eyes) by widening the punctal opening to allow the tears to drain with ease.

PROCEDURE3-snip punctoplasty and Mitomycin C

punctoplasty, more commonly known as watery eye surgery, is an ophthalmic surgical procedure performed to correct punctal stenosis (a condition that causes tears to overflow from the eyes) by widening the punctal opening to allow the tears to drain with ease. Mitomycin C is a chemotherapeutic agent that acts by inhibiting DNA synthesis

Sponsors

Al-Azhar University
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
16 Years to 63 Years
Healthy volunteers
No

Inclusion criteria

* Patients with recurrence of punctal stenosis at the end of 1 month following punctal dilatation.

Exclusion criteria

* patients with associated lacrimal passage obstruction

Design outcomes

Primary

MeasureTime frameDescription
Punctal patencyBaselinePunctum will be assessed by inspection of the lid by slitlamb examination, whither obstructed or not
Presence of EpiphoraBaselineIt will be assessed by inspection of the lid by slitlamb examination.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026