Hypoxia, Altitude
Conditions
Brief summary
This study analyses the impairment of colour vision during hypobaric hypoxia in volunteers of different groups.
Detailed description
This study analyses the impairment of colour vision during hypobaric hypoxia in volunteers of different groups. Five different Groups were analysed: * ground control binocular (n=12, Bi/GC) * ground control monocular (n=11, Mo/GC) * 10,000 ft, 60 min, monocular (n=10, Mo/60/10,000) * 15,000 ft, 15 min, binocular (n=11, Bi/15/15,000) * 15,000 ft, 60 min, monocular (n=10, Mo/60/15,000)
Interventions
OTHERHypobaric Hypoxia
The Waggoner Computerized Color Vision Test (WCCVT) and the Waggoner D-15 (WC-D15) were performed by 54 healthy volunteers in a decompression chamber.
Sponsors
Universitätsklinikum Köln
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)
Masking description
Volunteers
Intervention model description
Five different Groups were analyzed: * ground control binocular (n=12, Bi/GC) * ground control monocular (n=11, Mo/GC) * 10,000 ft, 60 min, monocular (n=10, Mo/60/10,000) * 15,000 ft, 15 min, binocular (n=11, Bi/15/15,000) * 15,000 ft, 60 min, monocular (n=10, Mo/60/15,000)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* volunteers from 18 years old
Exclusion criteria
* cardiovascular, pulmonary, neurological, or ear, nose, and throat disease * pregnant or suffering from cold symptoms
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Colour vision pre hypoxia monocular/binocular Waggoner CCVT | Assessment was conducted 15 minutes before the start of the hypoxia intervention and the number of correctly identified plates in the Waggoner CCVT was collected | Waggoner CCVT was administered in the pressure chamber pre hypoxia intervention, thereby the following parameters were collected: \- the number of correctly identified plates in the Waggoner CCVT as of the study arm 15,000 ft, 15 min, binocular the colour vision tests were performed binocularly as of the study arms 15,000 ft, 60 min, monocular and 10,000 ft, 60 min, monocular the colour vision tests were performed monocularly Time Frame - additional info: \- depending on the time the subjects took for the colour vision tests, the time between the end of the pre-test and the onset of hypoxia was slightly variable |
| Colour vision pre hypoxia monocular/binocular D15 | Assessment was conducted 15 minutes before the start of the hypoxia intervention and S-Index, C-Index and TES in the Waggoner D15 were collected | Waggoner D15 was administered in the pressure chamber pre hypoxia intervention, thereby the following parameters were collected: \- S-Index, C-Index and TES in the Waggoner D15 as of the study arm 15,000 ft, 15 min, binocular the colour vision tests were performed binocularly as of the study arms 15,000 ft, 60 min, monocular and 10,000 ft, 60 min, monocular the colour vision tests were performed monocularly Time Frame - additional info: depending on the time the subjects took for the colour vision tests, the time between the end of the pre-test and the onset of hypoxia was slightly variable |
| Colour vision during hypoxia monocular/binocular Waggoner CCVT | Assessment was conducted immediately or 45 minutes after induction of hypoxia and the number of correctly identified plates in the Waggoner CCVT was collected | Waggoner CCVT was administered in the pressure chamber during hypoxia intervention, thereby the following parameters were collected: \- the number of correctly identified plates in the Waggoner CCVT as of the study arm 15,000 ft, 15 min, binocular the colour vision tests were performed binocularly as of the study arms 15,000 ft, 60 min, monocular and 10,000 ft, 60 min, monocular the colour vision tests were performed monocularly Time Frame - additional info: * as of the study arm 15,000 ft, 15 min, binocular assessment was conducted immediately after onset of hypoxia * as of the study arms 15,000 ft, 60 min, monocular and 10,000 ft, 60 min, monocular assessment was conducted 45 minutes after onset of hypoxia * depending on the time the subjects took for the colour vision tests, the time between the end of the peri-test and the end of hypoxia was slightly variable |
| Colour vision during hypoxia monocular/binocular D15 | Assessment was conducted immediately or 45 minutes after induction of hypoxia and S-Index, C-Index and TES in the Waggoner D15 were collected | Waggoner D15 was administered in the pressure chamber during hypoxia intervention, thereby the following parameters were collected: \- S-Index, C-Index and TES in the Waggoner D15 as of the study arm 15,000 ft, 15 min, binocular the colour vision tests were performed binocularly as of the study arms 15,000 ft, 60 min, monocular and 10,000 ft, 60 min, monocular the colour vision tests were performed monocularly Time Frame - additional info: * as of the study arm 15,000 ft, 15 min, binocular assessment was conducted immediately after onset of hypoxia * as of the study arms 15,000 ft, 60 min, monocular and 10,000 ft, 60 min, monocular assessment was conducted 45 minutes after onset of hypoxia * depending on the time the subjects took for the colour vision tests, the time between the end of the peri-test and the end of hypoxia was slightly variable |
| Colour vision after hypoxia monocular/binocular Waggoner CCVT | Assessment was conducted immediately after hypoxia and the number of correctly identified plates in the Waggoner CCVT was collected | Waggoner CCVT was administered in the pressure chamber post hypoxia intervention, thereby the following parameters were collected: \- the number of correctly identified plates in the Waggoner CCVT as of the study arm 15,000 ft, 15 min, binocular the colour vision tests were performed binocularly as of the study arms 15,000 ft, 60 min, monocular and 10,000 ft, 60 min, monocular the colour vision tests were performed monocularly Time Frame - additional info: * as of the study arm 15,000 ft, 15 min, binocular assessment was conducted immediately after 15min of hypoxia * as of the study arms 15,000 ft, 60 min, monocular and 10,000 ft, 60 min, monocular assessment was conducted immediately after 60 minutes of hypoxia |
| Colour vision after hypoxia monocular/binocular D15 | Assessment was conducted immediately after hypoxia and S-Index, C-Index and TES in the Waggoner D15 were collected | Waggoner D15 was administered in the pressure chamber post hypoxia intervention, thereby the following parameters were collected: \- S-Index, C-Index and TES in the Waggoner D15 as of the study arm 15,000 ft, 15 min, binocular the colour vision tests were performed binocularly as of the study arms 15,000 ft, 60 min, monocular and 10,000 ft, 60 min, monocular the colour vision tests were performed monocularly Time Frame - additional info: * as of the study arm 15,000 ft, 15 min, binocular assessment was conducted immediately after 15min of hypoxia * as of the study arms 15,000 ft, 60 min, monocular and 10,000 ft, 60 min, monocular assessment was conducted immediately after 60 minutes of hypoxia |
| Colour vision without hypoxia monocular/binocular Waggoner CCVT | Assessment was coducted independently of hypoxia three times in a row with a 1 minute break in between each test and the number of correctly identified plates in the Waggoner CCVT was collected | Waggoner CCVT was administered three times in a row without hypoxia, thereby the following parameters were collected: \- the number of correctly identified plates in the Waggoner CCVT as of the study arm ground control binocular the colour vision tests were performed binocularly as of the study arm ground control monocular the colour vision tests were performed monocularly Time Frame - additional info: \- depending on the time the subjects took for each of the colour vision tests, total duration of all 3 test sequences can differ slightly |
| Colour vision without hypoxia monocular/binocular D15 | Assessment was coducted independently of hypoxia three times in a row with a 1 minute break in between each test, and S-Index, C-Index and TES in the Waggoner D15 were collected | Waggoner D15 was administered three times in a row without hypoxia, thereby the following parameters were collected: \- S-Index, C-Index and TES in the Waggoner D15 as of the study arm ground control binocular the colour vision tests were performed binocularly as of the study arm ground control monocular the colour vision tests were performed monocularly Time Frame - additional info: \- depending on the time the subjects took for each of the colour vision tests, total duration of all 3 test sequences can differ slightly |
Countries
Germany
Outcome results
None listed