Aerobic Exercise, Fat Burn, Resistance Exercise
Conditions
Brief summary
Purposes: The purpose of one-year project is to compare the effect of different intrasession exercise order of AE and RE during concurrent training on reducing VAT and improving insulin resistance for inactive middle-age community residents with obesity. Methods: Purposive sampling will be used to enroll community residents aged 40-64 years with inactive habit and body fat percentage ≧ 25% for male and ≧ 30% for female in southern Taiwan. Eligible participants will be stratified by sex and age (40-55years and 56-64 years) then block randomly divided into training group of AE preceding RE, RE preceding AE or a control group. The exercise training program will under supervision lasting 16 weeks with 3 times per week. The concurrent training prescription consist of AE 30 minutes and RE 15 minutes per session. A 5-minute interval between two exercise modalities. All participants will be evaluated outcomes for two time points including baseline (T0) and after 16-week intervention (T1). The primary outcomes are VAT and insulin resistance. A two-way ANOVA with repeated measures will be performed to compare changes of outcome variables over the intervention period. Relevance to clinical practice: The results of this project can assist health professionals to know how to properly prescribe concurrent training of AE and RE to achieve the greatest effects on VATreduction and insulin resistance improvement for middle-age residents with obesity.
Detailed description
Background: Visceral adipose tissue (VAT) accumulation is highly linking with cardiovascular diseases and insulin resistance. A combination of aerobic exercise (AE) and resistance exercise (RE) was an effective strategy to improve VAT and insulin resistance; however, no current evidence displayed whether the different orders of concurrent training (AE preceding RE or RE preceding AE) influence the effects on VAT reduction and insulin resistance improvement. Purposes: The purpose of one-year project is to compare the effect of different intrasession exercise order of AE and RE during concurrent training on reducing VAT and improving insulin resistance for inactive middle-age community residents with obesity. Methods: Purposive sampling will be used to enroll community residents aged 40-64 years with inactive habit and body fat percentage ≧ 25% for male and ≧ 30% for female in Tainan. Eligible participants will be stratified by sex and age (40-55years and 56-64 years) then block randomly divided into training group of AE preceding RE, RE preceding AE or a control group. The exercise training program will under supervision lasting 16 weeks with 3 times per week. The concurrent training prescription consist of AE 30 minutes and RE 15 minutes per session. A 5-minute interval between two exercise modalities. The control group will follow their primary lifestyle without exercise intervention. All participants will be evaluated outcomes for two time points including baseline (T0) and after 16-week intervention (T1). The primary outcomes are VAT and insulin resistance. VAT is measured by body composition analyzer and insulin resistance is calculate from fasting glucose and insulin level in blood samples. A two-way ANOVA with repeated measures will be performed to compare changes of outcome variables over the intervention period. Relevance to clinical practice: The results of this project can assist health professionals to know how to properly prescribe concurrent training of AE and RE to achieve the greatest effects on VATreduction and insulin resistance improvement for middle-age residents with obesity.
Interventions
BEHAVIORALaerobic exercise
The main AE program will be designed and controlled for at least moderate intensity of heart rate reserve (HRR) lasting 30 minutes. The goal of intensity will be set at least 40% of HRR during the first two weeks, and then progressively increase the targeted intensity at the end of 16 weeks with 60% HRR. The motions will design by involving core muscle training (e.g., march, step touch, lunge, V-step, box step, twist, knee up, scoop, and scissors).
BEHAVIORALresistance exercise
In the process, the participants will be instructed by resisting the weight smoothly, and peaking at hold. RE prescription consist of 2-4 sets with 10-15 repetitions per set with a rest interval of 1-2 minutes between sets to improve muscular fitness. The first two weeks will start with two sets of 10-15 repetitions and then gradually progress on four sets of 15 repetitions at the end of 16 weeks. The total duration of RE will lasting around 15 minutes.
Sponsors
National Tainan Junior College of Nursing
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Investigator, Outcomes Assessor)
Masking description
PI (data assessor) will be blinded for the grouping.
Eligibility
Sex/Gender
ALL
Age
40 Years to 64 Years
Healthy volunteers
Yes
Inclusion criteria
* 40 to 64 years old. * body fat percentage ≧ 25% for male and ≧ 30% for female. * with inactive habit (≤ 3 days of physical activity per week and ≤ 30 min per session). * can communicate in Mandarin or Taiwanese.
Exclusion criteria
* with recent unstable conditions in which had potential risk on exercise including stroke, cardiovascular and respiratory diseases, handicap, pregnancy. * with any contraindications to body composition analyzer measurement including body embed pacemakers and artificial metal joints, amputated hands or feet. * cannot corporate with either examination or intervention. * use psychotropic or appetite-regulating medicine. * under oral hopoglycemic agent or insulin treatment.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| visceral adipose tissue | at baseline | Participants will measure visceral adipose tissue measure at baseline by body composition analyzer. |
| Insulin | at baseline | Participants will collect insulin at baseline by blood samples |
| Fasting glucose | at baseline | Participants will collect fasting glucose at baseline by blood samples |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| waist circumference | at baseline | Participants will measure waist circumference at baseline by tape measurement |
| body fat percentage | at baseline | Participants will measure body fat percentage at baseline by body composition analyzer |
| hip circumference | at baseline | Participants will measure hip circumference at baseline by tape measurement |
| weight | at baseline | Participants will measure weight at baseline by body composition analyzer |
Countries
Taiwan
Outcome results
None listed