Autoimmune Polyendocrine Syndrome Type II
Conditions
Brief summary
Autoimmune polyendocrine syndrome (APS) is an autoimmune disease involving at least two endocrine organ. It is classified into type I and type II diseases. Among them, APS type II is more common. It is diagnosed when two of the three following diseases are diagnosed in the same patient, including type 1 diabetes mellitus, autoimmune thyroid disease, and primary adrenal insufficiency. In this study, we will observe the epidemiology, clinical characteristics, and genetic variants of APS II in Taiwan.
Interventions
OTHERno intervention
No intervention, only observation
Sponsors
National Taiwan University Hospital
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients visited NTUH during 2006-2021, and had at least two of the three diseases: type 1 DM, primary adrenal insufficiency, and autoimmune thyroid disease.
Exclusion criteria
* Patients aged less than 20 years old
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Rates of endocrine organs involved | 2022/1/1 ~ 2026/12/31 | We will observe the rate of each endocrine organ involved, including adrenal gland, thyroid, and pancreas |
Countries
Taiwan
Contacts
Primary ContactShyang-Rong Shih, MD, PhD
Outcome results
None listed