Analgesia
Conditions
Brief summary
• Neck pain and stiffness or sore throat, are common after anterior cervical spine surgery. Complications are rare but can be serious and even potentially life-threatening if they do occur. Rapid recovery and emergence from general anesthesia are important in cases of anterior cervical spine surgery.
Detailed description
* Null hypothesis (H0): No difference between the regional analgesia effects of bilateral ultrasound-guided superficial cervical plexus block and bilateral cervical erector spinae block in patients undergoing anterior cervical spine surgery under general anesthesia. * Alternative hypothesis (H1): There are differences between the regional analgesia effects of bilateral ultrasound-guided superficial cervical plexus block and bilateral cervical erector spinae block in
Interventions
PROCEDUREintermediate cervical plexus block
patients will receive bilateral ultrasound guided intermediate cervical plexus block using 15 ml of bupivacaine 0.25% for each side.
PROCEDURECervical Erector spinae block
patients will receive bilateral ultrasound guided cervical erector spinae plane block using 15 ml of bupivacaine 0.25% for each side at the level of C6.
Sponsors
Zagazig University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
21 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Patient acceptance. * Age (21-60) years old. * Both sex * American Society of Anesthesiologist physical status I / II * Elective anterior cervical spine surgery under general anesthesia. * patient With Body Mass Index (BMI) (25-35kg/m²)
Exclusion criteria
* Local infection at site of puncture. * Altered mental status. * History of allergy to study drugs ( bupivacaine, fentanyl). * Patients with chronic pain. * Patients with severe hepatic or kidney impairment. * Patients having a history of hematological disorders, including coagulation abnormality.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The time to first call to rescue analgesia | 24 hour postoperative | The time to first call to rescue analgesia (nalbuphine) the time between the end of surgery to first report of postoperative pain. will be recorded. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The total amount of nalbuphine | 24 hour postoperative | The total amount of nalbuphine given to each patient during the first 24h of postoperative period will be recorded |
| Pain intensity | up to 24hs postoperative | 2\. Pain intensity using Visual Analouge Scale (VAS) (11). A commonly used visual analog scale is a 10-cm line labeled with worst pain imaginable on the right border and no pain on the left border. The patient is instructed to make a mark along the line to represent the intensity of pain currently being experienced. VAS score will be assessed at 30 minutes, 2hs, 4hs, 6hs, 12hs, and 24hs postoperative and IV increment of 15mg nalbuphine (rescue analgesic) will be given if VAS≥4. |
| Total intra-operative fentanyl consumption | intra-operative | Total intra-operative fentanyl consumption by ug excluding induction dose. |
Countries
Egypt
Outcome results
None listed