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Combined Phacoemulsification and Diode Laser Therapy in Chronic Angle Closure Glaucoma

Combined Phacoemulsification and Different Modes of Diode Laser Therapy in Management of Chronic Angle Closure Glaucoma. A Comparative Study

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05576493
Enrollment
88
Registered
2022-10-12
Start date
2022-08-11
Completion date
2023-12-01
Last updated
2023-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Angle Closure Glaucoma

Keywords

angle closure glaucoma, cyclophotocoagulation

Brief summary

comparing different types of cuclophotocoagulation with cataract extraction to cataract extraction and goniocynechiolysis in cases of chronic angle closure glaucoma

Detailed description

Evaluation of the safety of MP-TSCPC , CW-TSCPC and endoscopic cyclophotocoagulation when combined with phacoemulsification in cases with CACG Comparing the efficacy of the combined procedures in control of the IOP and the success rate versus lens extraction combined with synechiolysis

Interventions

PROCEDUREphaco+MP-TSCPC

The procedure starts with performing the cyclophotocoagulation using the Micropulse P3 device (IQ 810 Laser Systems; Iridex, Mountain View, CA, USA) at 2500 mW with a duration of 90 seconds in each hemisphere at a 31.3% duty cycle under local anesthesia and then performing phacoemulsification and IOL implantation.

PROCEDUREphaco GSL

phacoemulsification will be done and then the angle is visualized by direct goniolens then the synechia are dissected by cohesive viscoelastic.

PROCEDUREphaco+TSCPC

The procedure starts with performing the cyclophotocoagulation using the IRIDEX's G probe device (IRIDEX Corp. Mountain View, CA, USA) at 1500 to2000 mW with a duration of 1500 ms applying about 15 shots in one hemisphere only under local anesthesia and then performing phacoemulsification and IOL implantation.

PROCEDUREphaco+endocyclophotocoagulation

phacoemulsification will be done and endocyclophotocoagulation will be done after cataract extraction

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
20 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

* Patients between 20 to 70 years chronic angle closure glaucoma

Exclusion criteria

* Patients in acute attack of angle closure. * Patients with previous filtering surgery or cycloablative procedure

Design outcomes

Primary

MeasureTime frameDescription
the percentage of intraocular pressure change6 Monthsmeasuring the intraocular pressure after 1M, 3M and 6M

Secondary

MeasureTime frameDescription
percent change of antiglaucoma medications6 Monthsthe number of medication before and after the procedure

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026