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Endoscopic Scoring System Utilization in Inflammatory Bowel Disease

Endoscopic Scoring System Utilization for Inflammatory Bowel Disease Activity Assessment

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05576402
Enrollment
1500
Registered
2022-10-12
Start date
2022-05-02
Completion date
2023-02-20
Last updated
2022-12-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inflammatory Bowel Diseases

Brief summary

Inflammatory bowel diseases comprise two distinctive entities: Crohn's disease and ulcerative colitis. During the last decade, endoscopic assessment of inflammation has become relevant since it is a prognostic factor. As a consequence, therapeutic targets now contemplate mucosal healing as part of the goals to be achieved. Endoscopic scores for Crohn's disease and ulcerative colitis have been developed to objectively assess the mucosal inflammatory activity. Although they may have some limitations, these scores have been widely accepted in referral centers, especially since they have been adopted as standard evaluation in inflammatory bowel disease clinical trials . However, their use in the setting of endoscopic practice outside centers with a high volume or with less experience in clinical trials is not known.

Interventions

PROCEDUREcolonoscopy

endoscopic exploration of colonic mucosa to evaluate inflammatory activity in patients with either Crohn's disease or ulcerative colitis

Sponsors

Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adult patients who underwent colonoscopy for the evaluation of mucosal inflammatory activity * Patients with an established diagnosis of either Crohn's disease or ulcerative colitis

Exclusion criteria

* Sigmoidoscopies performed in ulcerative colitis for the assessment of mucosal inflammatory activity

Design outcomes

Primary

MeasureTime frameDescription
Endoscopic score reportJanuary 2018-October 2022Proportion of colonoscopy reports among inflammatory bowel disease patients which include an endoscopic score to assess inflammatory activity

Countries

Argentina

Contacts

Primary ContactJuan S Lasa, MD
juanselasa@gmail.com541140848182

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026