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Dental Age Estimation by Different Methods in Patients With Cleft Lip and Palate

Evaluation of Dental Age of Children With Cleft Lip and Palate Using Willems Method, Cameriere European Formula, and London Atlas

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05573295
Enrollment
240
Registered
2022-10-10
Start date
2022-03-01
Completion date
2024-12-15
Last updated
2024-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cleft Lip and Palate, Dental Age Estimation

Keywords

children, dental age estimation, Cleft Lip and Palate, chronological age, London Atlas, Cameriere European Formula, Willems method

Brief summary

The aim of this study is to investigate whether there is a significant difference in dental age between children with CLP and healthy controls using the Willems method, Cameriere European formula and London Atlas. It is aimed to create a new formula if there is a significant difference in dental age between children with CLP and healthy controls.

Detailed description

Dental age is widely evaluated by pedodontists, forensic dentists and orthodontists. While a delay in tooth development may be associated with growth retardation and learning difficulties, dental age determination can also be used for forensic age determination for children whose birth information is uncertain. A clear assessment of maturation in children with continued growth is important in establishing a dental treatment plan. There are two basic approaches to dental age determination in children: evaluation of eruption of teeth in the oral cavity, evaluation of the development and mineralization of crowns and roots on dental radiographs. In many methods, the developmental stages of different numbers of permanent teeth are used. The most commonly used method for determining dental age in children; is the Demirjian method that evaluates the development of seven left permanent mandibular teeth in eight stages (from A to H). Willems et al. In 2001, they modified the Demirjian method by conducting a study on the fact that it showed higher age determination in the Belgian Caucasian population. The adapted method was named the Willems method. It is stated that one of the advantages of this method is that it is a relatively simple system for determining tooth age. One of the most widely used methods of dental age determination recently is the European formula of Cameriere et al., which is calculated based on open apex. It has been reported that this method has been tested on different population groups, and the results are accurate and reliable. An atlas method was proposed by a group of London researchers in 2010. The Atlas shows all the teeth array images of certain age groups as a schematic series. Age determination is made by deciding which reference image matches the individual's panoramic radiography image more.

Interventions

OTHERDiagnostic Test: Willems method

Willems method measures the developmental stages of the seven left permanent mandibular teeth and is frequently used for dental age estimation. The score of each stage is allocated, and the sum of the scores provides an evaluation of the subject's dental maturity.

OTHERDiagnostic Test: Cameriere method

Cameriere et al. designed a quantitative approach through a formula based on sex and the ratio between length and apex opening measurements of each lower left tooth.

OTHERDiagnostic Test: London Atlas method

The London Atlas requires the user to assess the tooth development and eruption and then match it to one of the 31 pictures of age categories.

Sponsors

Istanbul University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
5 Years to 14 Years
Healthy volunteers
Yes

Inclusion criteria

* 5-14 years old * Healthy children * Children with CLP * Patients without missing left mandibular permanent teeth on panoramic radiography

Exclusion criteria

* Children younger than 5 years old and older than 14 years (children that cannot be assessed by the Willems and Cameriere method) * Poor quality panoramic radiography * Patients who have received orthodontic treatment * Patients who received restorative or endodontic treatment

Design outcomes

Primary

MeasureTime frameDescription
Correlation coefficient of Willems methodday 1Dental age of children with Cleft Lip and Palate and healthy controls assessed by the correlation coefficient
Correlation coefficient of London Atlas method.day 1Dental age of children with Cleft Lip and Palate and healthy controls assessed by the correlation coefficient.
Correlation coefficient of Cameriere European formula.day 1Dental age of children with Cleft Lip and Palate and healthy controls assessed by the correlation coefficient.

Secondary

MeasureTime frameDescription
Dental age estimation in children with Cleft Lip and Palateday 1Dental age estimation in Turkish children

Countries

Turkey (Türkiye)

Contacts

Primary ContactYelda Kasimoglu Eldem, Assoc. Prof.
yelda.kasimoglu@istanbul.edu.tr00905336233978

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026