Detrusor Overactivity, Overactive Bladder, Overactive Bladder Syndrome
Conditions
Brief summary
In order to develop a test to diagnose overactive bladder from urine, it is essential that this test is at least as accurate as the tools that clinicians currently use. As such, this study will compare the performance of the device in development to the performance of existing methods.
Interventions
DIAGNOSTIC_TESTUrodynamics aka filling cystometry
Participants will be undergoing a routine diagnostic test to characterise bladder function and volume
Sponsors
South Tees Hospitals NHS Foundation Trust
Teesside University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* The participant is willing and able to give informed consent for participation in the study * The participant has been diagnosed with over-active bladder * Aged 18 years or above * Male or Female
Exclusion criteria
* The participant is unwilling to give informed consent for participation in the study * The participant is unable to represent their own interests or is particularly susceptible to coercion (i.e. is deemed as vulnerable) * The participant has been diagnosed with neurologic disease (stroke, MS, Parkinson's disease, spinal cord injury); history of uterine, cervical, vaginal or urethral cancer; history of cyclophosphamide use or any type of chemical cystitis; history of benign or malignant bladder tumours; has had Botulinum injections, neuromodulation or augmentation cystoplasty * Aged 17 years or younger.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Assessment of accuracy of a diagnostic test for overactive bladder | December 2022 - November 2023 | A prototype lateral flow immunoassay dipstick to detect specific urinary biomarkers for OAB, based on specific urinary biomarkers and with a dynamic range and sensitivity required for accurate OAB diagnosis. |
Outcome results
None listed